Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310177 | 0.85 | ESR2 (0.52) | ESR1ESR2ABHD6HTTHSP90AA1 | |
| SCHEMBL25604139 | 0.76 | ESR2 (0.49) | ESR2ABHD6HTT | |
| SCHEMBL31670368 | 0.75 | HDAC6 (0.55) | ESR1ESR2ABHD6HDAC8HDAC6 | |
| SCHEMBL25825898 | 0.75 | ESR1 (0.45) | ESR1ESR2ABHD6TRAP1HDAC8 | |
| SCHEMBL1295143 | 0.74 | ESR1 (0.41) | ESR1ESR2ABHD6 | |
| SCHEMBL7786861 | 0.73 | ESR1 (0.53) | ESR1ESR2ABHD6HSP90AA1HSP90AB1 | |
| SCHEMBL4416261 | 0.73 | ESR1 (0.36) | ESR1ESR2HTTPRKDC | |
| SCHEMBL25604135 | 0.72 | ESR2 (0.77) | ESR1ESR2ABHD6HSP90AA1HSP90AB1 | |
| SCHEMBL31733731 | 0.72 | PDK1 (0.45) | — | |
| SCHEMBL25202681 | 0.70 | ESR1 (0.46) | ESR1ESR2ABHD6HSP90AA1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |