Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 5/20 | 0.50 |
| ▸ | ADH1A | P07327 | 5/20 | 0.50 |
| ▸ | ADH1C | P00326 | 4/20 | 0.50 |
| ▸ | ADH7 | P40394 | 4/20 | 0.41 |
| ▸ | ADH4 | P08319 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146905 | 0.88 | ADH1B (0.46) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL28183645 | 0.83 | ADH1B (0.56) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL20374329 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL5932572 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL269153 | 0.77 | — | — | |
| SCHEMBL8628353 | 0.75 | ADH1B (0.50) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL13950294 | 0.75 | ADH1B (0.50) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL21337905 | 0.73 | ANPEP (0.36) | — | |
| SCHEMBL20860996 | 0.72 | ADH1B (0.43) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19775199 | 0.72 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724188-B1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2023-06-07 | — | — | EP | disclosed |