Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 8/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221694 | 1.00 | NR1H3 (0.40) | NR1H3NR1H2MEN1KMT2AEIF2AK4 | |
| SCHEMBL25606317 | 0.91 | NR1H2 (0.41) | NR1H3NR1H2EIF2AK4MAP4K4USP30 | |
| SCHEMBL29252894 | 0.91 | NR1H2 (0.41) | NR1H3NR1H2EIF2AK4MAP4K4USP30 | |
| SCHEMBL25251258 | 0.91 | NR1H2 (0.41) | NR1H3NR1H2EIF2AK4MAP4K4USP30 | |
| SCHEMBL25220207 | 0.86 | GPR119 (0.43) | NR1H3NR1H2MEN1KMT2AEIF2AK4 | |
| SCHEMBL38663567 | 0.78 | NR1H2 (0.48) | NR1H3NR1H2MEN1KMT2AEIF2AK4 | |
| SCHEMBL25263043 | 0.76 | GPR119 (0.45) | NR1H3NR1H2EIF2AK4TGM2MAP4K4 | |
| SCHEMBL29252847 | 0.76 | GPR119 (0.45) | NR1H3NR1H2EIF2AK4TGM2MAP4K4 | |
| SCHEMBL25606205 | 0.75 | NR1H2 (0.63) | NR1H3NR1H2MAPTMAP4K4USP30 | |
| SCHEMBL25216734 | 0.75 | NR1H2 (0.49) | NR1H3NR1H2MAPTMAP4K4USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101595-A1 | SORTILIN INHIBITORS | SORTINA PHARMA AB (SE) | 2023-06-08 | — | — | WO | disclosed |