Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | EPM2A | O95278 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254848 | 0.80 | GRM5 (0.45) | GRM5FFAR1PTGES | |
| SCHEMBL16638501 | 0.79 | GRM5 (0.45) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL30873473 | 0.76 | GRM5 (0.58) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL4174001 | 0.72 | GRM5 (0.49) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL12519881 | 0.72 | PRMT1 (0.57) | CACNA1GCACNA1B | |
| SCHEMBL27821982 | 0.71 | PTPN1 (0.60) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL8006286 | 0.70 | GRM5 (0.53) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL3937119 | 0.70 | GRM5 (0.47) | GRM5FFAR1PTGESPTPN1PTGDR2 | |
| SCHEMBL1477351 | 0.69 | GRM5 (0.52) | GRM5FFAR1PTGESPTPN1CHRNB2 | |
| SCHEMBL256660 | 0.68 | KCNH2 (0.39) | GRM5PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |