Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | EPM2A | O95278 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPRG | P23470 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967692 | 0.82 | KIF11 (0.36) | GRM5PTGESPTPN1PTGDR2PTPN6 | |
| SCHEMBL9967710 | 0.79 | GRM5 (0.46) | GRM5PTGESFFAR1 | |
| SCHEMBL256068 | 0.79 | GRM5 (0.44) | GRM5PTGESPTPN1FFAR1PTGDR2 | |
| SCHEMBL30873473 | 0.78 | GRM5 (0.58) | GRM5PTGESPTPN1FFAR1PTGDR2 | |
| SCHEMBL27821982 | 0.72 | PTPN1 (0.60) | GRM5PTGESPTPN1FFAR1PTGDR2 | |
| SCHEMBL8006286 | 0.71 | GRM5 (0.53) | GRM5PTGESPTPN1FFAR1PTGDR2 | |
| SCHEMBL8197656 | 0.71 | GRM5 (0.47) | GRM5PTGESPTPN1FFAR1PTGDR2 | |
| SCHEMBL1477351 | 0.70 | GRM5 (0.52) | GRM5PTGESPTPN1FFAR1 | |
| SCHEMBL18539930 | 0.70 | CYP1A2 (0.58) | — | |
| SCHEMBL9967728 | 0.68 | GRM5 (0.40) | GRM5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |