Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607375 | 0.85 | CYP11B2 (0.57) | CYP11B2CYP11B1PIM1CSNK2A1PIM3 | |
| SCHEMBL24088755 | 0.84 | CYP11B2 (0.48) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31676635 | 0.84 | CYP11B2 (0.48) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22490765 | 0.84 | CYP11B2 (0.44) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22490772 | 0.83 | NPC1 (0.41) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21392103 | 0.82 | CTPS1 (0.54) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21392101 | 0.82 | CTPS1 (0.53) | CYP11B2CYP11B1MET | |
| SCHEMBL29489098 | 0.82 | CTPS1 (0.53) | CYP11B2CYP11B1MET | |
| SCHEMBL30415999 | 0.82 | CTPS1 (0.54) | CYP11B2CYP11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30987732 | 0.80 | ABL1 (0.44) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183229-A1 | Compounds | SYGNATURE DISCOVERY LIMITED (GB) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183229-A1 | Compounds | UGT1A1, CYP1A1, CYP1B1 | CYP11B2 10/4885CYP11B1 9/4885NPC1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.