Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.49 |
| ▸ | JAK3 | P52333 | 11/20 | 0.45 |
| ▸ | LCK | P06239 | 9/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25593356 | 0.80 | BTK (0.59) | BTKJAK3LCKEGFR | |
| SCHEMBL25608245 | 0.78 | BTK (0.46) | BTKJAK3LCKEGFR | |
| SCHEMBL25607964 | 0.77 | BTK (0.42) | BTKJAK3LCKEGFR | |
| SCHEMBL25608157 | 0.76 | BTK (0.41) | BTKJAK3LCKEGFR | |
| SCHEMBL24411704 | 0.74 | BTK (0.65) | BTKJAK3LCKEGFR | |
| SCHEMBL24411709 | 0.74 | BTK (0.65) | BTKJAK3LCKEGFR | |
| SCHEMBL22359274 | 0.74 | BTK (0.53) | BTKJAK3LCKEGFR | |
| SCHEMBL25649437 | 0.73 | JAK3 (0.57) | BTKJAK3LCKEGFR | |
| SCHEMBL25607783 | 0.72 | JAK3 (0.40) | BTKJAK3LCKEGFR | |
| SCHEMBL18884592 | 0.72 | BTK (0.64) | BTKJAK3LCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |