Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220165 | 0.95 | APP (0.48) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL26229681 | 0.89 | APP (0.43) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL18220161 | 0.87 | APP (0.47) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL18220153 | 0.86 | APP (0.47) | APPALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL25605989 | 0.85 | APP (0.61) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL25610090 | 0.84 | APP (0.46) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL18220272 | 0.83 | APP (0.37) | APPALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17120674 | 0.83 | MAPT (0.37) | APPALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL18220156 | 0.83 | ALDH1A1 (0.56) | APPALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL25609494 | 0.82 | APP (0.39) | APPALDH1A1GAAMAPTSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |