Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 17/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25610167 | 0.88 | AXL (0.36) | — | |
| SCHEMBL25605775 | 0.87 | PLAT (0.54) | PLATRET | |
| SCHEMBL25605776 | 0.77 | CYP11B2 (0.43) | PLATRET | |
| SCHEMBL25610174 | 0.70 | MAPK14 (0.38) | — | |
| SCHEMBL25422693 | 0.65 | PLAT (0.56) | PLATRET | |
| SCHEMBL25420752 | 0.63 | CYP11B2 (0.50) | PLATRET | |
| SCHEMBL25271344 | 0.62 | CYP11B2 (0.46) | — | |
| SCHEMBL17738189 | 0.60 | PLAT (1.00) | PLAT | |
| SCHEMBL23047436 | 0.60 | MEN1 (0.39) | PLAT | |
| Hydrochloric Acid SCHEMBL17730430 | 0.59 | PLAT (0.98) | PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |