Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220182 | 0.91 | APP (0.43) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL18221450 | 0.89 | SYK (0.37) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL18220287 | 0.87 | LMNA (0.35) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL23134878 | 0.87 | APP (0.34) | APPPGR | |
| SCHEMBL17120884 | 0.85 | KDM4E (0.33) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL18220296 | 0.84 | KDM4E (0.33) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL20306979 | 0.84 | KDM4E (0.33) | APPMAPTKDM4ENSD2LMNA | |
| SCHEMBL18220166 | 0.83 | APP (0.42) | APPMAPTKDM4ETSHRCASP1 | |
| SCHEMBL18220176 | 0.82 | APP (0.43) | APPMAPTERN1ALDH1A1CTSL | |
| SCHEMBL25610291 | 0.82 | APP (0.38) | APPMAPTKDM4ENSD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |