Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220184 | 0.91 | APP (0.50) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24068143 | 0.89 | APP (0.45) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17120809 | 0.88 | APP (0.40) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL23134975 | 0.88 | APP (0.42) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17099878 | 0.88 | APP (0.55) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24075821 | 0.88 | APP (0.55) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17099866 | 0.88 | APP (0.55) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17099870 | 0.88 | APP (0.55) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL18220208 | 0.87 | APP (0.40) | APPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL23134977 | 0.85 | ALDH1A1 (0.48) | APPKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |