Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613029 | 0.81 | FEN1 (0.39) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL13604904 | 0.80 | CDK8 (0.39) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25613108 | 0.79 | ULK1 (0.39) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25613025 | 0.79 | FEN1 (0.37) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25613026 | 0.79 | FEN1 (0.42) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25625104 | 0.77 | ULK1 (0.45) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25613034 | 0.77 | FEN1 (0.37) | RIPK1FEN1KDRALDH1A1KDM4E | |
| SCHEMBL19367958 | 0.76 | FEN1 (0.36) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL16982068 | 0.76 | FEN1 (0.36) | RIPK1FEN1KDRFGFR1ULK1 | |
| SCHEMBL25613119 | 0.76 | FEN1 (0.36) | RIPK1FEN1KDRFGFR1ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | RIPK1 1106/4885FEN1 1864/4885KDR 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.