Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25418143 | 0.83 | XDH (0.42) | PDE10AXDHS1PR1S1PR5CSNK2A2 | |
| SCHEMBL25613352 | 0.83 | FGFR4 (0.41) | PDE10AUSP30XDHS1PR1S1PR5 | |
| SCHEMBL25605965 | 0.83 | XDH (0.42) | PDE10AXDHS1PR1S1PR5CSNK2A2 | |
| SCHEMBL25421541 | 0.80 | XDH (0.41) | PDE10AXDHS1PR1S1PR5CSNK2A2 | |
| SCHEMBL25612826 | 0.78 | XDH (0.43) | XDHS1PR1S1PR5CSNK2A2CSNK2A1 | |
| SCHEMBL25605336 | 0.77 | MKNK1 (0.59) | USP30XDHS1PR1S1PR5UCHL1 | |
| SCHEMBL25613441 | 0.77 | USP30 (0.41) | USP30XDHS1PR1S1PR5UCHL1 | |
| SCHEMBL25421729 | 0.74 | USP30 (0.41) | USP30XDHS1PR1S1PR5UCHL1 | |
| SCHEMBL25611032 | 0.74 | USP30 (0.43) | USP30XDHS1PR1S1PR5UCHL1 | |
| SCHEMBL25613444 | 0.74 | XDH (0.43) | USP30XDHS1PR1S1PR5UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |