SCHEMBL25614072

SCHEMBL25614072

CCCN(CCC)c1ccc2cc(-c3ccc(/C=C(\C#N)S(N)(=O)=O)s3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.39
MAPT P10636 2/20 0.38
SLC16A3 O15427 2/20 0.31
SLC16A1 P53985 2/20 0.31
ERN1 O75460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23134884 0.92 APP (0.40) APPMAPTERN1
SCHEMBL23134882 0.87 APP (0.40) APPMAPT
SCHEMBL18220266 0.85 MAPT (0.35) APPMAPT
SCHEMBL18220158 0.84 MAPT (0.36) APPMAPTSLC16A3SLC16A1
SCHEMBL23134338 0.83 APP (0.58) APPMAPTSLC16A3SLC16A1
SCHEMBL19294126 0.83 MAPT (0.35) APPMAPTSLC16A3SLC16A1
SCHEMBL17120683 0.83 MAPT (0.34) APPMAPT
SCHEMBL24075810 0.83 MAPT (0.33) APPMAPT
SCHEMBL20306972 0.81 MAPT (0.38) APPMAPT
SCHEMBL17120617 0.80 EGFR (0.41) APPMAPTSLC16A3SLC16A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3119761-B1 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME AMYDIS DIAGNOSTICS INC (US) 2023-06-07 EP disclosed