SCHEMBL24075810

SCHEMBL24075810

CCCN(CCC)c1ccc2cc(-c3ccc(/C=C(\C#N)S(=O)(=O)NC[C@@H](O)[C@@H](O)[C@H](O)CC)s3)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18220266 0.93 MAPT (0.35) MAPTAPP
SCHEMBL17120683 0.89 MAPT (0.34) MAPTAPP
SCHEMBL18220271 0.86 MAPT (0.36) MAPTAPP
SCHEMBL18220269 0.84 MAPT (0.36) MAPTAPP
SCHEMBL18220158 0.84 MAPT (0.36) MAPTAPP
SCHEMBL24075848 0.83
SCHEMBL19294126 0.83 MAPT (0.35) MAPTAPP
SCHEMBL25614072 0.83 APP (0.39) MAPTAPP
SCHEMBL17120673 0.83 MAPT (0.35) MAPTAPP
SCHEMBL18221579 0.80 MAPT (0.32) MAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369873-A1 COMPOSITIONS AND METHODS FOR DETECTION OF TRAUMATIC BRAIN INJURY Amydis, Inc. 2021-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369873-A1 COMPOSITIONS AND METHODS FOR DETECTION OF TRAUMATIC BRAIN INJURY S100B, FABP7, CRYAB MAPT 38/4885APP 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.