SCHEMBL25614196

SCHEMBL25614196

N/N=C(\N)c1cncc(N2CC3CC3C2)c1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 10/20 0.48
CHRNA3 P32297 10/20 0.48
CHRNB2 P17787 9/20 0.48
CHRNA4 P43681 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30556666 0.66 CHRNB2 (0.47) CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL1843614 0.65 CHRNB2 (0.51) CHRNB2CHRNA4
SCHEMBL30556707 0.60 CHRNB2 (0.70) CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL30837593 0.60 CHRNB2 (0.76) CHRNB2CHRNA4
SCHEMBL30811630 0.60 CHRNB2 (0.76) CHRNB2CHRNA4
SCHEMBL30811825 0.59 CHRNB2 (0.74) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL30811795 0.59 CHRNB2 (0.74) CHRNB2CHRNA4
SCHEMBL651641 0.59 CHRNB2 (0.56) CHRNB2CHRNA4
SCHEMBL14562446 0.59 ATM (0.51) CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL3538904 0.59 CHRNB4 (0.49) CHRNB4CHRNA3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104209-A1 METTL3 INHIBITOR COMPOUND 上海昂阔医药有限公司 2023-06-15 WO disclosed