SCHEMBL25614276

SCHEMBL25614276

Brc1cncc(N2CC3CC3C2)c1

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 14/20 0.67
CHRNA4 P43681 14/20 0.67
CHRNB4 P30926 13/20 0.67
CHRNA3 P32297 13/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6187377 0.84 CHRNB2 (0.70) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL30811682 0.81 CHRNB4 (0.58) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL4114802 0.80 CHRNB2 (0.57) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL4114754 0.80 CHRNB2 (0.57) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL11028141 0.79 CHRNB2 (0.56) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL6188155 0.78 CHRNB2 (0.58) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL649763 0.78 CHRNB2 (0.74) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL653211 0.78 CHRNB2 (0.74) CHRNB2CHRNA4CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL652485 0.77 CHRNB2 (0.72) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL6188295 0.75 CHRNB2 (0.58) CHRNB2CHRNA4CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104209-A1 METTL3 INHIBITOR COMPOUND 上海昂阔医药有限公司 2023-06-15 WO disclosed