Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15497176 | 0.82 | MEN1 (0.64) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11510867 | 0.82 | MAPT (0.68) | MAPTMEN1KMT2ACHRM2LMNA | |
| SCHEMBL11080258 | 0.81 | MAPT (0.52) | MAPTMEN1KMT2ACHRM2LMNA | |
| SCHEMBL855491 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11171070 | 0.76 | MAPT (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7946505 | 0.76 | CA12 (0.48) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2848441 | 0.75 | HDAC4 (0.55) | MAPTMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30874853 | 0.75 | HTT (0.61) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5542348 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2ACHRM2LMNA | |
| SCHEMBL10692338 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |