Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510867 | 0.88 | MAPT (0.68) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL5542348 | 0.84 | MAPT (0.46) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL15497176 | 0.84 | MEN1 (0.64) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL10055008 | 0.84 | MAPT (0.53) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL10055007 | 0.83 | ALDH1A1 (0.54) | MAPTHPGDALDH1A1HTTGAA | |
| SCHEMBL25614562 | 0.81 | MAPT (0.47) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL7946505 | 0.81 | CA12 (0.48) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL11171070 | 0.81 | MAPT (0.53) | MAPTHPGDALDH1A1LMNAGAA | |
| SCHEMBL10692338 | 0.80 | MAPT (0.46) | MAPTHPGDALDH1A1CHRM2LMNA | |
| SCHEMBL10018553 | 0.80 | RAB9A (0.69) | MAPTHPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113174056-B | Copper-containing coordination polymer based on asymmetric indole dicarboxylic acid, and preparation method and application thereof | 江南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-101691318-B | N-arylation method taking substituted adipic dihydrazide as ligand in aqueous phase system | UNIV SUN YAT SEN | 2013-05-29 | — | — | CN | disclosed |
| CN-101691318-A | N-arylation method taking substituted adipic dihydrazide as ligand in aqueous phase system | UNIV SUN YAT SEN | 2010-04-07 | — | — | CN | disclosed |
| EP-1901312-A1 | Electrical insulation system based on polybenzoxazine | ABB RESEARCH LTD. (CH) | 2008-03-19 | — | — | EP | disclosed |
| US-4469609-A | OXIDATION RESISTANCE | UNIROYAL, INC. (US) | 1984-09-04 | — | — | US | disclosed |
| US-4254087-A | Extraction of copper, nickel and cobalt using alkylaromatic sulfonic acids and chelating amines | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |