SCHEMBL25614790

SCHEMBL25614790

c1ccc2c(c1)-c1cc(-c3c4ccccc4c(-c4ccc5c(c4)oc4ccccc45)c4ccccc34)c3ccccc3c1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
AHR P35869 1/20 0.31
ALOX5 P09917 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25614652 0.88 PRKDC (0.31) PRKDCL3MBTL1
SCHEMBL25614777 0.88 AHR (0.32) PRKDCL3MBTL1AHRKDM4EMEN1
SCHEMBL24622587 0.88 PRKDC (0.32) PRKDCL3MBTL1AHRALOX5KDM4E
SCHEMBL24622816 0.87 MEN1 (0.35) PRKDCL3MBTL1AHRALOX5KDM4E
SCHEMBL24622569 0.87 AHR (0.33) PRKDCL3MBTL1AHRALOX5KDM4E
SCHEMBL24622832 0.86 PRKDC (0.32) PRKDCAHRALOX5KDM4EMEN1
SCHEMBL24622685 0.84 NPC1 (0.32) PRKDCL3MBTL1AHRKDM4EMEN1
SCHEMBL24622643 0.84 NPC1 (0.32) PRKDCL3MBTL1AHRKDM4EMEN1
SCHEMBL25614592 0.83 DUSP3 (0.31) AHRKDM4EALDH1A1MAPTHPGD
SCHEMBL25627813 0.83 PDK2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800792-B2 Organic compound with spirocyclic adamantane, and electronic element and electronic device using same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-24 US disclosed
US-11800792-B2 Organic compound with spirocyclic adamantane, and electronic element and electronic device using same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-24 US disclosed
US-20230200215-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230200215-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11800792-B2 Organic compound with spirocyclic adamantane, and electronic element and electronic device using same OR51E2, SQLE, ODC1 PRKDC 3105/4885L3MBTL1 4654/4885AHR 3908/4885
US-20230200215-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME LEF1, OCIAD1, OR10J3 PRKDC 2799/4885L3MBTL1 1678/4885AHR 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.