SCHEMBL25616038

SCHEMBL25616038

c1ccc(-c2cccc(-c3ccc(-n4c5ccccc5c5c(-c6ccccc6)cccc54)cc3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
ATM Q13315 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HDAC4 P56524 1/20 0.41
ALK Q9UM73 3/20 0.37
MAPK14 Q16539 1/20 0.37
KMT2A Q03164 3/20 0.36
IL1R1 P14778 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
PDE6D O43924 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23660363 0.97 L3MBTL1 (0.46) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL25617450 0.95 L3MBTL1 (0.50) L3MBTL1ATMKDM4EHDAC4MAPK14
SCHEMBL21708995 0.95 L3MBTL1 (0.50) L3MBTL1ATMKDM4EHDAC4MAPK14
SCHEMBL15502543 0.93 L3MBTL1 (0.46) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL23660353 0.92 L3MBTL1 (0.52) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL28317204 0.92 L3MBTL1 (0.55) L3MBTL1ATMKDM4EHDAC4MAPK14
SCHEMBL20633262 0.92 L3MBTL1 (0.49) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL19769540 0.92 L3MBTL1 (0.45) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL25941544 0.92 KDM4E (0.45) L3MBTL1ATMKDM4EHDAC4ALK
SCHEMBL19769532 0.92 L3MBTL1 (0.45) L3MBTL1ATMKDM4EHDAC4ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198020-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2023-06-21 EP disclosed