⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25616363 | 0.79 | — | — | |
| SCHEMBL1908509 | 0.73 | — | — | |
| SCHEMBL28780092 | 0.72 | LMNA (0.34) | — | |
| SCHEMBL30040170 | 0.71 | — | — | |
| SCHEMBL6521631 | 0.71 | TDP1 (0.41) | — | |
| SCHEMBL20901392 | 0.69 | — | — | |
| SCHEMBL16754685 | 0.69 | — | — | |
| SCHEMBL20412554 | 0.69 | TDP1 (0.38) | — | |
| SCHEMBL14813893 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28780013 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091554-A1 | NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS | ICAGEN, LLC (US) | 2023-05-25 | — | — | WO | disclosed |