Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559239 | 0.90 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL10387979 | 0.87 | HPGD (0.56) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL15330011 | 0.87 | TSHR (0.50) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2562001 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2560069 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2562281 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2562835 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2558838 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL2557983 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL11781754 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |