Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.68 |
| ▸ | PPARA | Q07869 | 12/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231218 | 0.88 | SMN1; SMN2 (0.63) | PPARGPPARASMN1; SMN2KMT2A | |
| Methane SCHEMBL27838357 | 0.86 | SMN1; SMN2 (0.61) | PPARGPPARASMN1; SMN2KMT2A | |
| SCHEMBL1532659 | 0.85 | SMN1; SMN2 (0.59) | PPARGPPARASMN1; SMN2POLBKMT2A | |
| SCHEMBL4730249 | 0.85 | SMN1; SMN2 (0.59) | PPARGPPARASMN1; SMN2MAPTRAB9A | |
| SCHEMBL11550284 | 0.84 | SMN1; SMN2 (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL7716884 | 0.83 | SMN1; SMN2 (0.58) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL19489229 | 0.83 | SMN1; SMN2 (0.58) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL19486253 | 0.83 | SMN1; SMN2 (0.58) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL29384572 | 0.83 | PPARG (0.52) | PPARGPPARASMN1; SMN2MAPTHPGD | |
| SCHEMBL19486247 | 0.83 | SMN1; SMN2 (0.58) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| EP-1994055-A2 | ANTI-5T4 ANTIBODIES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007106744-A2 | ANTI-5T4 ANTIBODIES AND USES THEREOF | WYETH (US) | 2007-09-20 | — | — | WO | disclosed |