Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 13/20 | 0.51 |
| ▸ | PPARA | Q07869 | 13/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539449 | 0.87 | PPARG (0.60) | SMN1; SMN2PPARGPPARAMAPTL3MBTL1 | |
| SCHEMBL5010216 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARAL3MBTL1NPC1 | |
| SCHEMBL2231218 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARGPPARAHTT | |
| SCHEMBL2561889 | 0.85 | PPARG (0.68) | SMN1; SMN2PPARGPPARAMAPTL3MBTL1 | |
| Methane SCHEMBL27838357 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2PPARGPPARAHTT | |
| SCHEMBL5004494 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGPPARAL3MBTL1NPC1 | |
| SCHEMBL1532659 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARAALDH1A1 | |
| SCHEMBL4895944 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11550284 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL19486253 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |