Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687229 | 0.82 | PIK3CD (0.42) | CYP2D6SMN1; SMN2PIK3CDSMYD3HRH3 | |
| SCHEMBL1272200 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2RORCSMYD3HRH3SMO | |
| SCHEMBL12726845 | 0.77 | CYP2D6 (0.47) | CYP2D6SMN1; SMN2PIK3CDRORCHRH3 | |
| SCHEMBL8242487 | 0.77 | HRH3 (0.38) | CYP2D6RORCSMYD3HRH3KCNH2 | |
| SCHEMBL21107430 | 0.76 | PIK3CD (0.43) | CYP2D6SMN1; SMN2PIK3CDHRH3KDM4E | |
| SCHEMBL12439743 | 0.74 | NCF1 (0.48) | RORCHRH3ALDH1A1SMO | |
| SCHEMBL1621207 | 0.74 | PIK3CD (0.42) | CYP2D6SMN1; SMN2PIK3CDHRH3KDM4E | |
| SCHEMBL24005324 | 0.73 | CYP2D6 (0.44) | CYP2D6SMN1; SMN2PIK3CDRORCCCR4 | |
| SCHEMBL599158 | 0.72 | NCF1 (0.52) | CYP2D6SMN1; SMN2PIK3CDHRH3KDM4E | |
| SCHEMBL13683795 | 0.72 | PIK3CD (0.44) | CYP2D6SMN1; SMN2PIK3CDHRH3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |