SCHEMBL256196

SCHEMBL256196

COC(CC#N)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27685737 0.97
SCHEMBL15134508 0.84
SCHEMBL15134504 0.84
SCHEMBL6803911 0.82
SCHEMBL17889057 0.78 TSHR (0.33)
SCHEMBL17889056 0.78 LMNA (0.31)
SCHEMBL3613980 0.75
SCHEMBL21863060 0.75
SCHEMBL1227367 0.73
SCHEMBL15134573 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457215-B Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2022-08-23 CN claimed
EP-4034529-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE -(1H)-ONE Adama Makhteshim Ltd. (IL) 2022-08-03 EP claimed
CN-114599639-A Process for the preparation of 5- (fluoro-4-imino-3-methyl) -1-tosyl-3, 4-dihydropyrimidin- (1H) -one 阿达玛马克西姆有限公司 2022-06-07 CN claimed
WO-2021059160-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE -(1H)-ONE ADAMA MAKHTESHIM LTD. (IL) 2021-04-01 WO claimed
CN-112457215-A Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2021-03-09 CN claimed
CN-109485638-B Preparation method of oxitinib intermediate 新发药业有限公司 2020-07-17 CN claimed
CN-109485638-A A kind of uncommon preparation method for Buddhist nun's intermediate difficult to understand 新发药业有限公司 2019-03-19 CN claimed
CN-105294564-B A kind of synthetic method of 5 amino 1 (2 ethoxy) pyrazoles 山东铂源药业有限公司 2018-01-23 CN claimed
CN-105294564-A Synthetic method of 5-amino-1-(2-hydroxyethyl)pyrazole SHANDONG BOYUAN PHARMACEUTICAL CO LTD 2016-02-03 CN claimed
CN-103145626-B Method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde UNIV SHANDONG 2015-02-11 CN claimed
CN-102731395-B Intermediate compound of antitumor drug neratinib and its preparation method and use SHANGHAI INST MATERIA MEDICA 2015-02-04 CN claimed
CN-102123981-B The preparation methods of 6-substituted amino-3-cyanoquinoline and the intermediates thereof TOPHARMAN SHANGHAI Co.,Ltd. (CN) 2014-10-01 CN claimed
US-8481741-B2 Preparation methods of 6 substituted amino-3 cyanoquinoline compounds and the intermediates thereof TOPHARMAN SHANGHAI CO., LTD. (CN) 2013-07-09 US claimed
CN-103145626-A Method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde UNIV SHANDONG 2013-06-12 CN claimed
CN-102731395-A Intermediate compound of antitumor drug neratinib and its preparation method and use SHANGHAI INST MATERIA MEDICA 2012-10-17 CN claimed
US-20110263860-A1 PREPARATION METHODS OF 6-SUBSTITUTED AMINO-3-CYANOQUINOLINE COMPOUNDS AND THE INTERMEDIATES THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2011-10-27 US claimed
CN-101723854-A Preparation method of 6-substituted amino-3-cyano quinoline compound and midbody thereof SHANGHAI TOPHARMAN CO LTD 2010-06-09 CN claimed
US-5932676-A ORGANOSILICON POLYMERS; STORAGE STABILITY; COATINGS FOR ELECTRONICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-08-03 US claimed
EP-0814130-A2 Liquid coating composition for forming silicon-containing coating film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-29 EP claimed
JP-58026855-A None JP disclosed
US-12617786-B2 Dihydro-cyclopenta-isoquinoline sulfonamides derivatives UCB Biopharma SRL (BE) 2026-05-05 US disclosed
EP-4081295-B1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2026-04-29 EP disclosed
US-12595265-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2026-04-07 US disclosed
US-20260092041-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE-(1H)-ONE AND DERIVATIVES OF THE COMPOUND ADAMA MAKHTESHIM LTD. (IL) 2026-04-02 US disclosed
US-12466796-B2 Process for preparing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1H)-one and derivatives of the compound ADAMA MAKHTESHIM LTD. (IL) 2025-11-11 US disclosed
US-12006294-B2 Therapeutic compounds REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2024-06-11 US disclosed
US-20240158398-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2024-05-16 US disclosed
US-20240092773-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2024-03-21 US disclosed
CN-117658902-A Method for preparing 4-trifluoromethyl nicotinic acid 内蒙古源宏精细化工有限公司 2024-03-08 CN disclosed
EP-4285996-A2 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE Blueprint Medicines Corporation (US) 2023-12-06 EP disclosed
US-11820773-B2 Tricyclic compounds ALIGOS THERAPEUTICS, INC. (US) 2023-11-21 US disclosed
US-11820773-B2 Tricyclic compounds ALIGOS THERAPEUTICS, INC. (US) 2023-11-21 US disclosed
US-11820773-B2 Tricyclic compounds ALIGOS THERAPEUTICS, INC. (US) 2023-11-21 US disclosed
CN-117088885-A Triazolopyridazine compound and application thereof 上海赛默罗生物科技有限公司 2023-11-21 CN disclosed
CN-111757940-B Microbiological method for producing amides 哥伦比亚有限公司 2023-11-07 CN disclosed
EP-4251625-A1 TRICYCLIC COMPOUNDS Aligos Therapeutics, Inc. (US) 2023-10-04 EP disclosed
CN-112638899-B Preparation and application of aromatic compound with immunoregulation function 上海轶诺药业有限公司 2023-09-05 CN disclosed
EP-3442977-B1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORP (US) 2023-06-28 EP disclosed
US-20230143040-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE-(1H)-ONE AND DERIVATIVES OF THE COMPOUND ADAMA MAKHTESHIM LTD. (IL) 2023-05-11 US disclosed
US-11634422-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2023-04-25 US disclosed
CN-112851588-B Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same 复旦大学 2023-04-21 CN disclosed
US-11572363-B2 Substituted bicyclic pyrimidine compounds with tubulin and multiple receptor inhibition DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2023-02-07 US disclosed
CN-110437107-B Acrylketoxime ester compound, preparation method and composition 江苏裕事达新材料科技有限责任公司 2022-11-08 CN disclosed
EP-4081295-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2022-11-02 EP disclosed
US-20220315585-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2022-10-06 US disclosed
EP-3710592-B1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA S R L (IT) 2022-08-31 EP disclosed
CN-114980975-A Dihydrocyclopentaisoquinoline sulfonamide derivatives UCB生物制药有限责任公司 2022-08-30 CN disclosed
CN-112457215-B Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2022-08-23 CN disclosed
CN-112457215-B Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2022-08-23 CN disclosed
CN-112457215-B Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2022-08-23 CN disclosed
EP-4034529-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE -(1H)-ONE Adama Makhteshim Ltd. (IL) 2022-08-03 EP disclosed
CN-114599639-A Process for the preparation of 5- (fluoro-4-imino-3-methyl) -1-tosyl-3, 4-dihydropyrimidin- (1H) -one 阿达玛马克西姆有限公司 2022-06-07 CN disclosed
WO-2022115384-A1 TRICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2022-06-02 WO disclosed
US-20220169650-A1 TRICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. 2022-06-02 US disclosed
US-20220169650-A1 TRICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. 2022-06-02 US disclosed
WO-2022115384-A1 TRICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2022-06-02 WO disclosed
US-11261468-B2 Microbiological process for the preparation of amides COLUMBIA SRL (IT) 2022-03-01 US disclosed
CN-109311889-B Activin receptor-like kinase inhibitors 缆图药品公司 2021-11-16 CN disclosed
CN-113646302-A Method for producing tetracarboxylic dianhydride 本州化学工业株式会社 2021-11-12 CN disclosed
US-20210347785-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) 2021-11-11 US disclosed
US-20210347785-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) 2021-11-11 US disclosed
CN-113135857-A Synthesis method of N-hydroxyethyl-5-amino-1H pyrazole 杭州迪克科技有限公司 2021-07-20 CN disclosed
WO-2021130257-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2021-07-01 WO disclosed
US-20210188858-A1 Substituted Bicyclic Pyrimidine Compounds with Tubulin and Multiple Receptor Inhibition DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2021-06-24 US disclosed
EP-3831823-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) 2021-06-09 EP disclosed
CN-112851588-A Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same 复旦大学 2021-05-28 CN disclosed
US-10995075-B2 Process for producing fluorocytosine and fluorocytosine derivatives UNIVERSITY OF DURHAM 2021-05-04 US disclosed
CN-112638899-A Preparation and application of aromatic compound with immunoregulation function 上海轶诺药业有限公司 2021-04-09 CN disclosed
WO-2021059160-A1 PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE -(1H)-ONE ADAMA MAKHTESHIM LTD. (IL) 2021-04-01 WO disclosed
CN-106795123-B Fluorocytosine and fluorocytosine derivatives 杜伦大学 2021-03-16 CN disclosed
CN-112457215-A Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2021-03-09 CN disclosed
CN-112457215-A Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2021-03-09 CN disclosed
CN-112457215-A Synthetic method of 3, 3-dimethoxypropionitrile 上海诺哈尔化工技术有限公司 2021-03-09 CN disclosed
US-10906910-B2 Substituted bicyclic pyrimidine compounds with tubulin and multiple receptor inhibition DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2021-02-02 US disclosed
CN-112062780-A Preparation and application of aromatic compound with immunoregulation function 上海轶诺药业有限公司 2020-12-11 CN disclosed
WO-2020218134-A1 METHOD FOR PRODUCING TETRACARBOXYLIC ACID DIANHYDRIDE 本州化学工業株式会社 2020-10-29 WO disclosed
CN-111757940-A Microbiological method for producing amides 哥伦比亚有限公司 2020-10-09 CN disclosed
EP-3710592-A1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES Columbia S.r.l. (IT) 2020-09-23 EP disclosed
US-20200248216-A1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA SRL (IT) 2020-08-06 US disclosed
US-20200248216-A1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA SRL (IT) 2020-08-06 US disclosed
CN-109485638-B Preparation method of oxitinib intermediate 新发药业有限公司 2020-07-17 CN disclosed
US-10669277-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2020-06-02 US disclosed
US-20200095207-A1 Process for Producing Fluorocytosine and Fluorocytosine Derivatives UNIVERSITY OF DURHAM (GB) 2020-03-26 US disclosed
CN-110790770-A Preparation and application of aromatic amine compound with immunoregulation function 上海轶诺药业有限公司 2020-02-14 CN disclosed
WO-2020025030-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION 上海轶诺药业有限公司 2020-02-06 WO disclosed
WO-2020025030-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION 上海轶诺药业有限公司 2020-02-06 WO disclosed
US-20200031830-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION (US) 2020-01-30 US disclosed
CN-110437107-A A kind of propylene ketooxime ester compounds, preparation method and composition YOUDI NEW MATERIAL TECH SUZHOU CO LTD 2019-11-12 CN disclosed
US-20190330157-A1 THERAPEUTIC COMPOUNDS REGENTS OF THE UNIVERSITY OF MINNESOTA 2019-10-31 US disclosed
US-20190300538-A1 Substituted Bicyclic Pyrimidine Compounds with Tubulin and Multiple Receptor Inhibition Duquesne University of the Holy Spirt 2019-10-03 US disclosed
EP-3125899-B1 SUBSTITUTED BICYCLIC PYRIMIDINE COMPOUNDS WITH TUBULIN AND MULTIPLE RECEPTOR INHIBITION UNIV HOLY GHOST DUQUESNE (US) 2019-10-02 EP disclosed
US-10365750-B2 Transparent conductive film and method for producing same, information input device, and electronic device DEXERIALS CORPORATION (JP) 2019-07-30 US disclosed
US-10358450-B2 Substituted bicyclic pyrimidine compounds with tubulin and multiple receptor inhibition Duquesne University of the Holy Spirt (US) 2019-07-23 US disclosed
EP-3186231-B1 PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES UNIV DURHAM (GB) 2019-07-10 EP disclosed
CN-105960402-B Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2019-06-28 CN disclosed
CN-105960685-B Transparent conductive film, method for manufacturing same, information input device, and electronic device 迪睿合电子材料有限公司 2019-06-25 CN disclosed
US-10233186-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2019-03-19 US disclosed
CN-109485638-A A kind of uncommon preparation method for Buddhist nun's intermediate difficult to understand 新发药业有限公司 2019-03-19 CN disclosed
EP-3442977-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE Blueprint Medicines Corporation (US) 2019-02-20 EP disclosed
CN-109311889-A Activin receptor-like kinase inhibitors 蓝图药品公司 2019-02-05 CN disclosed
EP-3102570-B1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-01-02 EP disclosed
US-10100208-B2 Method of manufacturing a transparent conductive film DEXERIALS CORPORATION (JP) 2018-10-16 US disclosed
US-9963598-B2 Transparent conductive film, information input device, and electronic device DEXERIALS CORPORATION (JP) 2018-05-08 US disclosed
CN-105960298-B Metal nanometer line, nesa coating and its manufacture method, dispersion liquid, message input device and electronic equipment 迪睿合电子材料有限公司 2018-04-20 CN disclosed
US-20180065177-A1 METAL NANOWIRES, TRANSPARENT CONDUCTIVE FILM AND METHOD FOR PRODUCING SAME, DISPERSION LIQUID, INFORMATION INPUT DEVICE, AND ELECTRONIC DEVICE DEXERIALS CORPORATION (JP) 2018-03-08 US disclosed
CN-105294564-B A kind of synthetic method of 5 amino 1 (2 ethoxy) pyrazoles 山东铂源药业有限公司 2018-01-23 CN disclosed
CN-105294564-B A kind of synthetic method of 5 amino 1 (2 ethoxy) pyrazoles 山东铂源药业有限公司 2018-01-23 CN disclosed
EP-3251674-A2 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES BioCryst Pharmaceuticals, Inc. (US) 2017-12-06 EP disclosed
US-20170298028-A1 Process for Producing Fluorocytosine and Fluorocytosine Derivatives UNIVERSITY OF DURHAM (GB) 2017-10-19 US disclosed
WO-2017181117-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION (US) 2017-10-19 WO disclosed
US-20170298069-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2017-10-19 US disclosed
CN-106795123-A Fluorocytosine and fluorocytosine derivatives 杜伦大学 2017-05-31 CN disclosed
US-9650371-B2 Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity SHIONOGI & CO., LTD. (JP) 2017-05-16 US disclosed
CN-104350053-B Heteroaromatic methyl Cycloamine derivative 大正制药株式会社 2017-03-08 CN disclosed
US-9586969-B2 Microbiocidal heterobicyclic derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-03-07 US disclosed
EP-3125899-A1 SUBSTITUTED BICYCLIC PYRIMIDINE COMPOUNDS WITH TUBULIN AND MULTIPLE RECEPTOR INHIBITION Duquesne University of the Holy Spirit (US) 2017-02-08 EP disclosed
US-9556135-B2 Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use AMGEN, INC. (US) 2017-01-31 US disclosed
US-20170010736-A1 TRANSPARENT CONDUCTIVE FILM AND METHOD FOR PRODUCING SAME, INFORMATION INPUT DEVICE, AND ELECTRONIC DEVICE DEXERIALS CORPORATION (JP) 2017-01-12 US disclosed
EP-2862860-B1 1,3-OXAZOLIDINE OR 1,3-OXAZINANE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS TAISHO PHARMACEUTICAL CO LTD (JP) 2016-12-21 EP disclosed
EP-2613328-B1 TRANSPARENT ELECTROCONDUCTIVE FILM, INFORMATION INPUT DEVICE, AND ELECTRONIC INSTRUMENT DEXERIALS CORP (JP) 2016-12-14 EP disclosed
EP-3102570-A1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES Syngenta Participations AG (CH) 2016-12-14 EP disclosed
US-20160355518-A1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2016-12-08 US disclosed
US-20160346839-A1 METAL NANOWIRES, TRANSPARENT CONDUCTIVE FILM AND METHOD FOR PRODUCING SAME, DISPERSION LIQUID, INFORMATION INPUT DEVICE, AND ELECTRONIC DEVICE DEXERIALS CORPORATION (JP) 2016-12-01 US disclosed
US-20160326158-A1 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY SHIONOGI & CO (JP) 2016-11-10 US disclosed
EP-2014163-B1 LIQUID COMPOSITION, PROCESS FOR PRODUCTION OF THE LIQUID COMPOSITION, AND ECTOPARASITE CONTROLLING AGENT FOR USE IN MAMMALS AND AVIANS NIPPON SODA CO (JP) 2016-09-28 EP disclosed
CN-105960402-A Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2016-09-21 CN disclosed
CN-105960298-A Metal nanowire, transparent conductive film and production method for same, fluid dispersion, information input device, and electronic machine 迪睿合电子材料有限公司 2016-09-21 CN disclosed
US-20160129114-A1 LIQUID COMPOSITION, PROCESS FOR PRODUCING THE LIQUID COMPOSITION, AND ECTOPARASITE CONTROLLING AGENT FOR USE IN MAMMALS AND AVIANS NIPPON SODA CO (JP) 2016-05-12 US disclosed
US-20160108052-A1 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY SHIONOGI & CO (JP) 2016-04-21 US disclosed
US-9309263-B2 Fused multi-cyclic sulfone compounds as inhibitors of beta-secretase and methods of use thereof AMGEN INC. (US) 2016-04-12 US disclosed
CN-105473667-A Thiol group-containing colored compound, metal nanowire, dispersion, transparent conductive film, information input device, and electronic device DEXERIALS CORP 2016-04-06 CN disclosed
CN-103004012-B Photo-electric conversion element electrolyte and use this electrolytical photo-electric conversion element and DSSC THE YOKOHAMA RUBBER CO.,LTD. (JP) 2016-03-23 CN disclosed
US-9287056-B2 Electrolyte for photoelectric conversion element, photoelectric conversion element using the electrolyte, and dye-sensitized solar cell using the electrolyte THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-03-15 US disclosed
US-9277746-B2 Liquid composition, process for producing the liquid composition, and ectoparasite controlling agent for use in mammals and avians NIPPON SODA CO., LTD. (JP) 2016-03-08 US disclosed
US-9273053-B2 Sulfur-containing heterocyclic derivative having Beta secretase inhibitory activity SHIONOGI & CO., LTD. (JP) 2016-03-01 US disclosed
US-9266870-B2 Heteroaromatic methyl cyclic amine derivative TAISHO PHARMACEUTICAL CO., LTD (JP) 2016-02-23 US disclosed
CN-105294564-A Synthetic method of 5-amino-1-(2-hydroxyethyl)pyrazole SHANDONG BOYUAN PHARMACEUTICAL CO LTD 2016-02-03 CN disclosed
CN-105294564-A Synthetic method of 5-amino-1-(2-hydroxyethyl)pyrazole SHANDONG BOYUAN PHARMACEUTICAL CO LTD 2016-02-03 CN disclosed
US-20150291596-A1 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES BIOCRYST PHARMACEUTICALS, INC. 2015-10-15 US disclosed
WO-2015153955-A1 SUBSTITUTED BICYCLIC PYRIMIDINE COMPOUNDS WITH TUBULIN AND MULTIPLE RECEPTOR INHIBITION DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2015-10-08 WO disclosed
WO-2015153955-A1 SUBSTITUTED BICYCLIC PYRIMIDINE COMPOUNDS WITH TUBULIN AND MULTIPLE RECEPTOR INHIBITION DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2015-10-08 WO disclosed
US-20150284398-A1 Substituted Bicyclic Pyrimidine Compounds with Tubulin and Multiple Receptor Inhibition DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2015-10-08 US disclosed
US-20150284398-A1 Substituted Bicyclic Pyrimidine Compounds with Tubulin and Multiple Receptor Inhibition DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2015-10-08 US disclosed
US-20150259308-A1 AMINO-DIHYDROTHIAZINE AND AMINO-DIOXIDO DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE ANTAGONISTS AND METHODS OF USE AMGEN INC. (US) 2015-09-17 US disclosed
US-20150252059-A1 BRIDGED BICYCLIC AMINO THIAZINE DIOXIDE COMPOUNDS AS INHIBITORS OF BETA-SECRETASE AND METHODS OF USE THEREOF AMGEN INC (US) 2015-09-10 US disclosed
US-9112094-B2 Copper tin sulfide and copper zinc tin sulfide ink compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-18 US disclosed
WO-2015117563-A1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2015-08-13 WO disclosed
EP-2102172-B1 SYNTHESIS OF 4-AMINO-PYRIMIDINES DSM IP ASSETS BV (NL) 2015-08-12 EP disclosed
US-9105796-B2 CZTS/Se precursor inks and methods for preparing CZTS/Se thin films and CZTS/Se-based photovoltaic cells E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-11 US disclosed
US-9096605-B2 Pyrazolopyrimidine derivatives as PI3 kinase inhibitors GLAXOSMITHKLINE LLC (US) 2015-08-04 US disclosed
US-9096605-B2 Pyrazolopyrimidine derivatives as PI3 kinase inhibitors GLAXOSMITHKLINE LLC (US) 2015-08-04 US disclosed
US-9096615-B2 Bridged bicyclic amino thiazine dioxide compounds as inhibitors of beta-secretase and methods of use thereof AMGEN INC. (US) 2015-08-04 US disclosed
US-20150183768-A1 HETEROAROMATIC METHYL CYCLIC AMINE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-07-02 US disclosed
US-20150166798-A1 TRANSPARENT CONDUCTIVE FILM, INFORMATION INPUT DEVICE, AND ELECTRONIC DEVICE DEXERIALS CORP (JP) 2015-06-18 US disclosed
US-20150166797-A1 TRANSPARENT CONDUCTIVE FILM, INFORMATION INPUT DEVICE, AND ELECTRONIC DEVICE DEXERIALS CORP (JP) 2015-06-18 US disclosed
US-20150118144-A1 DISPERSIBLE METAL CHALCOGENIDE NANOPARTICLES E I DU PONT NEMOURS AND COMPANY (US) 2015-04-30 US disclosed
EP-2862860-A1 HETEROAROMATIC METHYL CYCLIC AMINE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2015-04-22 EP disclosed
US-20150105379-A1 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY SHIONOGI & CO., LTD. (JP) 2015-04-16 US disclosed
US-8957305-B2 Electrolyte for photoelectric conversion element, and photoelectric conversion element and dye-sensitized solar cell using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-02-17 US disclosed
CN-103145626-B Method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde UNIV SHANDONG 2015-02-11 CN disclosed
CN-104350053-A Heteroaromatic methyl cyclic amine derivative TAISHO PHARMACEUTICAL CO LTD 2015-02-11 CN disclosed
US-20150038497-A1 BRIDGED BICYCLIC AMINO THIAZINE DIOXIDE COMPOUNDS AS INHIBITORS OF BETA-SECRETASE AND METHODS OF USE THEREOF AMGEN INC. 2015-02-05 US disclosed
WO-2015017407-A1 BRIDGED BICYCLIC AMINO THIAZINE DIOXIDE COMPOUNDS AS INHIBITORS OF BETA- SECRETASE AMGEN INC. (US) 2015-02-05 WO disclosed
CN-102731395-B Intermediate compound of antitumor drug neratinib and its preparation method and use SHANGHAI INST MATERIA MEDICA 2015-02-04 CN disclosed
EP-1238704-B1 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEM (JP) 2015-01-21 EP disclosed
CN-102229605-B N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase MSD ITALY SRL 2015-01-14 CN disclosed
CN-103435556-B Simple and quick method for synthesizing improved vitamin B1 intermediate 2-methyl-4-amino-5-aminomethylpyrimidine XINFA PHARMACEUTICAL CO LTD 2014-11-26 CN disclosed
CN-102123981-B The preparation methods of 6-substituted amino-3-cyanoquinoline and the intermediates thereof TOPHARMAN SHANGHAI Co.,Ltd. (CN) 2014-10-01 CN disclosed
CN-104059023-A Environment-friendly preparation method for key intermediate 2-methyl-4-amino-5-aminomethyl pyrimidine of vitamin B1 XINFA PHARMACEUTICAL CO LTD 2014-09-24 CN disclosed
WO-2014120658-A1 FUSED MULTICYCLIC 3-AMINO-5,6-DIHYDRO-2H-1,4-THIAZINE DERIVATIVES AND THEIR USE AS BETA-SECRETASE INHIBITORS AMGEN INC. (US) 2014-08-07 WO disclosed
US-20140213581-A1 FUSED MULTI-CYCLIC SULFONE COMPOUNDS AS INHIBITORS OF BETA-SECRETASE AND METHODS OF USE THEREOF AMGEN INC. 2014-07-31 US disclosed
US-20140187545-A1 Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors GLAXOSMITHKLINE LLC (US) 2014-07-03 US disclosed
US-20140187545-A1 Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors GLAXOSMITHKLINE LLC (US) 2014-07-03 US disclosed
CN-102633680-B Catalyst for preparing 3,3-diethoxyl propionitrile and preparation method of catalyst UNIV LANGZHOU 2014-06-11 CN disclosed
US-20140144500-A1 SEMICONDUCTOR INKS FILMS, COATED SUBSTRATES AND METHODS OF PREPARATION E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-29 US disclosed
US-8735048-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film using the composition and pattern forming method FUJIFILM CORPORATION (JP) 2014-05-27 US disclosed
US-8735048-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film using the composition and pattern forming method FUJIFILM CORPORATION (JP) 2014-05-27 US disclosed
US-8735048-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film using the composition and pattern forming method FUJIFILM CORPORATION (JP) 2014-05-27 US disclosed
WO-2014078778-A2 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES BIOCRYST PHARMACEUTICALS, INC. (US) 2014-05-22 WO disclosed
WO-2014059185-A1 AMINO - DIHYDROTHIAZINE AND AMINO - DIOXIDO DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE ANTAGONISTS AND METHODS OF USE AMGEN INC. (US) 2014-04-17 WO disclosed
US-20140107109-A1 AMINO-DIHYDROTHIAZINE AND AMINO-DIOXIDO DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE ANTAGONISTS AND METHODS OF USE AMGEN INC. 2014-04-17 US disclosed
US-8637504-B2 Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity SHIONOGI & CO., LTD. (JP) 2014-01-28 US disclosed
EP-1666440-B1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-01-22 EP disclosed
CN-103435556-A Simple and quick method for synthesizing improved vitamin B1 intermediate 2-methyl-4-amino-5-aminomethylpyrimidine XINFA PHARMACEUTICAL CO LTD 2013-12-11 CN disclosed
CN-103420918-A Simple and convenient preparation method of key intermediate (2-methyl-4-amino-5-amino methyl pyrimidine) for vitamin B1 XINFA PHARMACEUTICAL CO LTD 2013-12-04 CN disclosed
WO-2013172949-A1 DISPERSIBLE METAL CHALCOGENIDE NANOPARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-21 WO disclosed
EP-1433527-B1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS DAICEL CHEM (JP) 2013-11-06 EP disclosed
EP-2307355-B1 Novel synthesis of substituted 4-amino-pyrimidines DSM IP ASSETS BV (NL) 2013-11-06 EP disclosed
US-20130264526-A1 MOLECULAR PRECURSORS AND PROCESSES FOR PREPARING COPPER INDIUM GALLIUM SULFIDE/SELENIDE COATINGS AND FILMS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-10 US disclosed
US-20130233202-A1 INKS AND PROCESSES FOR PREPARING COPPER INDIUM GALLIUM SULFIDE/SELENIDE COATINGS AND FILMS EI DU PONT DE NEMOURS AND COMPANY (US) 2013-09-12 US disclosed
US-20130206235-A1 ELECTROLYTE FOR PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT AND DYE-SENSITIZED SOLAR CELL USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-08-15 US disclosed
WO-2013108891-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME 三菱化学株式会社 (JP) 2013-07-25 WO disclosed
CN-103221471-A Semiconductor inks, films, coated substrates and methods of preparation DU PONT 2013-07-24 CN disclosed
EP-2613328-A1 TRANSPARENT ELECTROCONDUCTIVE FILM, INFORMATION INPUT DEVICE, AND ELECTRONIC INSTRUMENT Dexerials Corporation (JP) 2013-07-10 EP disclosed
US-8481741-B2 Preparation methods of 6 substituted amino-3 cyanoquinoline compounds and the intermediates thereof TOPHARMAN SHANGHAI CO., LTD. (CN) 2013-07-09 US disclosed
US-20130146143-A1 ELECTROLYTE FOR PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION ELEMENT USING THE ELECTROLYTE, AND DYE-SENSITIZED SOLAR CELL USING THE ELECTROLYTE THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-06-13 US disclosed
CN-103145626-A Method for synthesizing 4-amino-2-(methylmercapto) pyrimidine-5-formaldehyde UNIV SHANDONG 2013-06-12 CN disclosed
CN-102219750-B N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ANGELETTI P IST RICHERCHE BIO 2013-05-29 CN disclosed
US-20130125988-A1 CZTS/Se PRECURSOR INKS AND METHODS FOR PREPARING CZTS/Se THIN FILMS AND CZTS/Se-BASED PHOTOVOLTAIC CELLS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-23 US disclosed
CN-101626835-B Immobilized cyclic imide catalyst and process for oxidation of organic compounds with the same DAICEL CHEM 2013-04-24 CN disclosed
CN-101431892-B Liquid composition and preparation method thereof, exterior parasite remover for mammal and birds NIPPON SODA CO 2013-03-27 CN disclosed
WO-2013028263-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2013-02-28 WO disclosed
CN-102834774-A Actinic ray-sensitive or radiation-sensitive resin composition, resist film using same, and pattern formation method FUJIFILM CORP 2012-12-19 CN disclosed
EP-2529276-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD FUJIFILM Corporation (JP) 2012-12-05 EP disclosed
US-20120301817-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301817-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301817-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
CN-102731395-A Intermediate compound of antitumor drug neratinib and its preparation method and use SHANGHAI INST MATERIA MEDICA 2012-10-17 CN disclosed
US-8252927-B2 Synthesis of substituted 4-amino-pyrimidines DSM IP ASSETS B.V. (NL) 2012-08-28 US disclosed
CN-102633680-A Catalyst for preparing 3,3-diethoxyl propionitrile and preparation method of catalyst UNIV LANGZHOU 2012-08-15 CN disclosed
US-8198443-B2 Synthesis of 4-amino-pyrimidines scaffolds DSM IP ASSETS B.V. (NL) 2012-06-12 US disclosed
WO-2012075259-A1 MOLECULAR PRECURSORS AND PROCESSES FOR PREPARING COPPER INDIUM GALLIUM SULFIDE/SELENIDE COATINGS AND FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-07 WO disclosed
WO-2012075267-A1 INKS AND PROCESSES FOR PREPARING COPPER INDIUM GALLIUM SULFIDE/SELENIDE COATINGS AND FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-07 WO disclosed
WO-2012071288-A1 SEMICONDUCTOR INKS, FILMS, COATED SUBSTRATES AND METHODS OF PREPARATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-31 WO disclosed
CN-102439097-A Copper tin sulfide and copper zinc tin sulfide ink compositions DU PONT 2012-05-02 CN disclosed
CN-102439096-A Processes for preparing copper tin sulfide and copper zinc tin sulfide films DU PONT 2012-05-02 CN disclosed
US-20120061628-A1 COPPER TIN SULFIDE AND COPPER ZINC TIN SULFIDE INK COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-15 US disclosed
US-20120060928-A1 PROCESSES FOR PREPARING COPPER TIN SULFIDE AND COPPER ZINC TIN SULFIDE FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-15 US disclosed
WO-2012028756-A1 PREPARATION OF SUBSTITUTED PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE COMPOUNDS INSTITUT QUÍMIC DE SARRIÀ CETS, FUNDACIÓ PRIVADA (ES) 2012-03-08 WO disclosed
CN-102229605-A N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ANGELETTI P IST RICHERCHE BIO 2011-11-02 CN disclosed
US-20110263860-A1 PREPARATION METHODS OF 6-SUBSTITUTED AMINO-3-CYANOQUINOLINE COMPOUNDS AND THE INTERMEDIATES THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2011-10-27 US disclosed
CN-102219750-A N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ANGELETTI P IST RICHERCHE BIO 2011-10-19 CN disclosed
CN-1835922-B Process for preparing 4-aryl-nicotinamide derivatives HOFFMANN LA ROCHE 2011-08-31 CN disclosed
CN-102149718-A Fused heterocyclic compound LG LIFE SCIENCES LTD (KR) 2011-08-10 CN disclosed
US-7994330-B2 Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-09 US disclosed
US-20110190279-A1 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY SHIONOGI & CO., LTD. (JP) 2011-08-04 US disclosed
WO-2011093520-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2011-08-04 WO disclosed
US-20110178300-A1 NOVEL SYNTHESIS OF SUBSTITUTED 4-AMINO-PYRIMIDINES DSM IP ASSETS B.V. (NL) 2011-07-21 US disclosed
US-20110166121-A1 FUSED HETEROCYCLIC COMPOUND LG LIFE SCIENCES LTD. (KR) 2011-07-07 US disclosed
EP-2334689-A2 FUSED HETEROCYCLIC COMPOUND LG Life Sciences Ltd. (KR) 2011-06-22 EP disclosed
CN-1700918-B N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ANGELETTI P IST RICHERCHE BIO 2011-06-08 CN disclosed
CN-102066337-A 5-hydroxypyrimidine-4-carboxamide compounds DAIICHI SANKYO CO LTD 2011-05-18 CN disclosed
US-20110112103-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-05-12 US disclosed
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
EP-2307355-A1 Novel synthesis of substituted 4-amino-pyrimidines DSM IP Assets B.V. (NL) 2011-04-13 EP disclosed
US-20110034449-A1 N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2011-02-10 US disclosed
US-20100317869-A1 IMMOBILIZED CYCLIC IMIDE CATALYST AND PROCESS FOR OXIDATION OF ORGANIC COMPOUNDS WITH THE SAME DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-16 US disclosed
US-7820660-B2 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2010-10-26 US disclosed
US-7759515-B2 Catalyst comprising N-substituted cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-07-20 US disclosed
US-7741514-B2 Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-22 US disclosed
CN-101723854-A Preparation method of 6-substituted amino-3-cyano quinoline compound and midbody thereof SHANGHAI TOPHARMAN CO LTD 2010-06-09 CN disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
WO-2010027236-A2 FUSED HETEROCYCLIC COMPOUND LG LIFE SCIENCES LTD. (KR) 2010-03-11 WO disclosed
WO-2010010113-A1 Novel synthesis of substituted 4-amino-pyrimidines DSM IP ASSETS B.V. (NL) 2010-01-28 WO disclosed
US-20100016591-A1 SYNTHESIS OF 4-AMINO-PYRIMIDINES SCAFFOLDS DSM IP ASSETS B.V. (NL) 2010-01-21 US disclosed
CN-101626835-A Immobilized cyclic imide catalyst and process for oxidation of organic compounds with the same DAICEL CHEM 2010-01-13 CN disclosed
US-20090306100-A1 METHODS OF TREATING SCHIZOPHRENIA LEXICON PHARMACEUTICALS, INC. 2009-12-10 US disclosed
US-20090306100-A1 METHODS OF TREATING SCHIZOPHRENIA LEXICON PHARMACEUTICALS, INC. 2009-12-10 US disclosed
US-20090306380-A1 Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde UBE INDUSTRIES, LTD. (JP) 2009-12-10 US disclosed
EP-2116303-A1 IMMOBILIZED CYCLIC IMIDE CATALYST AND PROCESS FOR OXIDATION OF ORGANIC COMPOUNDS WITH THE SAME Daicel Chemical Industries, Ltd. (JP) 2009-11-11 EP disclosed
US-7608727-B2 Process for the preparation of furan compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-27 US disclosed
EP-2102172-A1 SYNTHESIS OF 4-AMINO-PYRIMIDINES DSM IP Assets B.V. (NL) 2009-09-23 EP disclosed
EP-1460071-B1 N-HETEROARYLNICOTINAMIDE DERIVATIVES MITSUI CHEMICALS AGRO INC (JP) 2009-09-16 EP disclosed
CN-100537031-C Processes for production of organic compounds DAICEL CHEM (JP) 2009-09-09 CN disclosed
EP-2089018-A2 METHODS OF TREATING COGNITIVE IMPAIRMENT AND DEMENTIA Lexicon Pharmaceuticals, Inc. (US) 2009-08-19 EP disclosed
CN-101431892-A Liquid composition and its preparation method, exterior parasite remover for mammal and birds NIPPON SODA CO (JP) 2009-05-13 CN disclosed
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20090069386-A1 Liquid Composition, Process for Producing the Liquid Composition,and Ectoparasite Controlling Agent for Use in Mammals and Avians NIPPON SODA CO., LTD. (JP) 2009-03-12 US disclosed
EP-2014163-A1 LIQUID COMPOSITION, PROCESS FOR PRODUCTION OF THE LIQUID COMPOSITION, AND ECTOPARASITE CONTROLLING AGENT FOR USE IN MAMMALS AND AVIANS Nippon Soda Co., Ltd. (JP) 2009-01-14 EP disclosed
US-7476741-B2 Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2009-01-13 US disclosed
US-7476741-B2 Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2009-01-13 US disclosed
US-7476741-B2 Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2009-01-13 US disclosed
EP-1664051-A4 PYRROLOPYRIDAZINE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS BRISTOL MYERS SQUIBB CO (US) 2008-12-31 EP disclosed
US-20080275004-A1 N-Substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase MSD ITALIA S.R.L. (IT) 2008-11-06 US disclosed
CN-100425609-C N-Heteroaryl Nicotinamide Derivatives SANKYO AGRO CO LTD (JP) 2008-10-15 CN disclosed
US-7435734-B2 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2008-10-14 US disclosed
EP-1972620-A1 Synthesis of 4-amino-pyrimidines DSMIP Assets B.V. (NL) 2008-09-24 EP disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
CN-101252935-A Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions containing them, and methods of their use LEXICON GENETICS INC (US) 2008-08-27 CN disclosed
WO-2008087021-A1 SYNTHESIS OF 4-AMINO-PYRIMIDINES DSM IP ASSETS B.V. (NL) 2008-07-24 WO disclosed
CN-100404479-C Method for producing aromatic unsaturated compound SUMITOMO CHEMICAL CO (JP) 2008-07-23 CN disclosed
US-20080171881-A1 Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-07-17 US disclosed
US-20080153811-A1 methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia. LEXICON PHARMACEUTICALS, INC. 2008-06-26 US disclosed
US-20080153811-A1 methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia. LEXICON PHARMACEUTICALS, INC. 2008-06-26 US disclosed
WO-2008067121-A2 METHODS OF TREATING COGNITIVE IMPAIRMENT AND DEMENTIA LEXICON PHARMACEUTICALS, INC. (US) 2008-06-05 WO disclosed
WO-2008067121-A2 METHODS OF TREATING COGNITIVE IMPAIRMENT AND DEMENTIA LEXICON PHARMACEUTICALS, INC. (US) 2008-06-05 WO disclosed
EP-1919482-A1 PYRROLOPYRIDINE, PYRROLOPYRIMIDINE AND PYRAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE Lexicon Pharmaceuticals, Inc. (US) 2008-05-14 EP disclosed
US-7368615-B2 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-05-06 US disclosed
CN-101166713-A Process for producing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde UBE INDUSTRIES (JP) 2008-04-23 CN disclosed
CN-101151238-A Method for producing organic compound and method for decomposing compound having dicarboxyimide skeleton DAICEL CHEM (JP) 2008-03-26 CN disclosed
EP-1870394-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND METHOD FOR DECOMPOSING COMPOUND HAVING DICARBOXYIMIDE SKELETON Daicel Chemical Industries, Ltd. (JP) 2007-12-26 EP disclosed
EP-1656351-B1 PROCESS FOR PREPARATION OF 4-ARYL-NICOTINAMIDE DERIVATIVES HOFFMANN LA ROCHE (CH) 2007-12-19 EP disclosed
US-7288649-B2 Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-10-30 US disclosed
US-7288658-B2 Process for preparation of pyridine derivatives HOFFMANN-LA ROCHE INC. (US) 2007-10-30 US disclosed
US-7288658-B2 Process for preparation of pyridine derivatives HOFFMANN-LA ROCHE INC. (US) 2007-10-30 US disclosed
US-7288658-B2 Process for preparation of pyridine derivatives HOFFMANN-LA ROCHE INC. (US) 2007-10-30 US disclosed
US-20070244241-A1 Resin Composition NISSHINBO INDUSTRIES, INC. (JP) 2007-10-18 US disclosed
EP-1826202-A1 Process for the preparation of furan compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-08-29 EP disclosed
US-20070197806-A1 Process for the preparation of furan compounds DAICEL CHEMICAL INDUSTRIES, LTD. 2007-08-23 US disclosed
US-7256304-B2 Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these UBE INDUSTRIES, LTD. (JP) 2007-08-14 US disclosed
US-20070123524-A1 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase MSD ITALIA S.R.L. (IT) 2007-05-31 US disclosed
CN-1318393-C Process for the preparation of 4-haloalkylnicotinonitriles BAYER CROPSCIENCE GMBH (DE) 2007-05-30 CN disclosed
US-7217713-B2 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ISTITUTO DI RICHERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2007-05-15 US disclosed
WO-2007024789-A1 PYRROLOPYRIDINE, PYRROLOPYRIMIDINE AND PYRAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE LEXICON GENETICS INCORPORATED (US) 2007-03-01 WO disclosed
WO-2007024789-A1 PYRROLOPYRIDINE, PYRROLOPYRIMIDINE AND PYRAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE LEXICON GENETICS INCORPORATED (US) 2007-03-01 WO disclosed
US-20070049608-A1 Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions comprising them, and methods of their use LEXICON PHARMACEUTICALS, INC. 2007-03-01 US disclosed
US-20070049608-A1 Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions comprising them, and methods of their use LEXICON PHARMACEUTICALS, INC. 2007-03-01 US disclosed
US-7169780-B2 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ISTITUTE DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2007-01-30 US disclosed
US-20060281629-A1 Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst ISHII YASUTAKA 2006-12-14 US disclosed
CN-1871188-A Method for producing aromatic unsaturated compound SUMITOMO CHEMICAL CO (JP) 2006-11-29 CN disclosed
WO-2006124897-A2 METHODS AND COMPOSITIONS FOR IMPROVING COGNITION LEXICON GENETICS INCORPORATED (US) 2006-11-23 WO disclosed
US-20060258860-A1 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase MSD ITALIA S.R.L. (IT) 2006-11-16 US disclosed
US-20060258691-A1 Methods and compositions for improving cognition LEXICON PHARMACEUTICALS, INC. 2006-11-16 US disclosed
CN-1284775-C Process for producing 3-unsubstituted-5-amino-4-nitrosopyrazole compound, 2-hydroxyimino-3-oxopropanenitrile, 3-hydrazono-2-hydroxyimino propanenitrile compound, and process for producing these compounds UBE INDUSTRIES (JP) 2006-11-15 CN disclosed
US-20060229196-A1 Catalyst comprising n-substituted cyclic imide compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-10-12 US disclosed
US-7115541-B2 Catalyst comprising n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-10-03 US disclosed
CN-1835922-A Process for preparing 4-aryl-nicotinamide derivatives HOFFMANN LA ROCHE (CH) 2006-09-20 CN disclosed
CN-1272105-C Catalysts comprising N-substituted cyclic imides and processes for prepairing organic compounds with catalysts DAICEL CHEM (JP) 2006-08-30 CN disclosed
US-7094906-B2 Processes for preparing pesticidal intermediates Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) 2006-08-22 US disclosed
US-7091342-B2 Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-7084090-B2 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-01 US disclosed
CN-1264607-C Catalysts comprised of N-substituted cyclic imides and processes for preparing organic compounds with catalysts DAICEL CHEM (JP) 2006-07-19 CN disclosed
EP-1664051-A2 PYRROLOPYRIDAZINE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Bristol-Myers Squibb Company (US) 2006-06-07 EP disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed
EP-1656351-A1 PROCESS FOR PREPARATION OF 4-ARYL-NICOTINAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2006-05-17 EP disclosed
US-7030112-B2 Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders BRISTOL-MYERS SQUIBB COMPANY (US) 2006-04-18 US disclosed
US-7015236-B2 N-heteroarylnicotinamide derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2006-03-21 US disclosed
CN-1244560-C Process for preparing 4-haloalkyl nicotinonitriles BAY CROPSCIENCE GMBH (DE) 2006-03-08 CN disclosed
EP-1441735-B1 N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE ANGELETTI P IST RICHERCHE BIO (IT) 2006-02-22 EP disclosed
CN-1243027-C Polymerization process KANEGAFUCHI CHEMICAL IND (JP) 2006-02-22 CN disclosed
CN-1736982-A Process for the preparation of 4-haloalkylnicotinonitriles BAYER CROPSCIENCE GMBH (DE) 2006-02-22 CN disclosed
US-20060036100-A1 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-02-16 US disclosed
US-6998491-B2 Catalyst comprising a cyclic imide compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-02-14 US disclosed
US-20060030716-A1 Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-02-09 US disclosed
CN-1700918-A N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ANGELETTI P IST RICHERCHE BIO (IT) 2005-11-23 CN disclosed
CN-1692111-A N-Heteroaryl Nicotinamide Derivatives SANKYO AGRO CO LTD (JP) 2005-11-02 CN disclosed
US-6946554-B2 Process for the preparation of 9-deazaguanine derivatives BIOCRYST PHARMACEUTICALS, INC. (US) 2005-09-20 US disclosed
US-20050176750-A1 Substituted 4h-chromens, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2005-08-11 US disclosed
CN-1620436-A Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these UBE INDUSTRIES (JP) 2005-05-25 CN disclosed
US-20050096472-A1 Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these UBE INDUSTRIES, LTD. (JP) 2005-05-05 US disclosed
EP-1090930-B1 POLYMERIZATION METHOD KANEKA CORP (JP) 2005-05-04 EP disclosed
CN-1607980-A Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same DAICEL CHEM (JP) 2005-04-20 CN disclosed
WO-2005030144-A2 PYRROLOPYRIDAZINE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-04-07 WO disclosed
EP-1513515-A2 SUBSTITUTED 4H-CHROMENES, 2H-CHROMENES, CHROMANS AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF Cytovia, Inc. (US) 2005-03-16 EP disclosed
US-6864385-B2 Process for the preparation of 4-haloalkylnicotinonitriles AVENTIS CROPSCIENCE GMBH (DE) 2005-03-08 US disclosed
WO-2005014549-A1 PROCESS FOR PREPARATION OF 4-ARYL-NICOTINAMIDE DERIVATIVES F. HOFFMANN-LA-ROCHE AG (CH) 2005-02-17 WO disclosed
US-20050025774-A1 N-substituted hydroxypyrimidinone carboxamide inhibitors of hiv integrase MSD ITALIA S.R.L. (IT) 2005-02-03 US disclosed
US-20050020439-A1 Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
US-20050014792-A1 Process for preparation of pyridine derivatives ROCHE PALO ALTO LLC 2005-01-20 US disclosed
US-20050004368-A1 N-heteroarylnicotinamide derivatives SANKYO ARGO COMPANY LIMITED (JP) 2005-01-06 US disclosed
US-20040254181-A1 Process for the preparation of 9-deazaguanine derivatives BIOCRYST PHARMACEUTICALS, INC. 2004-12-16 US disclosed
EP-1073627-B1 PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES BAYER AGRICULTURE LTD (GB) 2004-12-01 EP disclosed
EP-1475369-A1 PROCESS FOR PRODUCING 3-UNSUBSTITUTED 5-AMINO-4-NITROSOPYRAZOLE COMPOUND, AND 2-HYDROXYIMINO-3-OXOPROPIONITRILE, 3-HYDRAZONO-2-HYDROXYIMINOPROPIONITRILE COMPOUND, AND PROCESSES FOR PRODUCING THESE Ube Industries, Ltd. (JP) 2004-11-10 EP disclosed
US-20040209886-A1 Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders BRISTOL-MYERS SQUIBB COMPANY 2004-10-21 US disclosed
US-20040198985-A1 Processes for preparing pesticidal intermediates AVENTIS AGRICULTURE LTD. (GB) 2004-10-07 US disclosed
EP-1459804-A1 CATALYSTS COMPRISING CYCLIC ACYLUREA COMPOUNDS AND PROCESSES FOR PRODUCTION OF ORGANIC COMPOUNDS WITH THE SAME Daicel Chemical Industries, Ltd. (JP) 2004-09-22 EP disclosed
EP-1460071-A1 N-HETEROARYLNICOTINAMIDE DERIVATIVES Sankyo Agro Company, Limited (JP) 2004-09-22 EP disclosed
EP-1441735-A1 N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2004-08-04 EP disclosed
CN-1158249-C Processes for preparing pesticidal intermediates ��������ũҵ�� 2004-07-21 CN disclosed
EP-1433527-A1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2004-06-30 EP disclosed
US-20040053778-A1 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-03-18 US disclosed
CN-1479723-A Process for preparing 4-haloalkyl nicotinonitriles �Ϻ���ͨ��ѧ 2004-03-03 CN disclosed
CN-1476352-A Catalysts comprised of N-substituted cyclic imides and processes for preparing organic compounds with catalysts ����贻�ѧ��ҵ��ʽ���� 2004-02-18 CN disclosed
US-20040010145-A1 Heterocyclylalkylazole derivatives and their use as pesticides SCHAPER WOLFGANG (DE) 2004-01-15 US disclosed
US-6673956-B2 INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE AVENTIS AGRICULTURE LTD. (GB) 2004-01-06 US disclosed
WO-2003096982-A2 SUBSTITUTED 4H-CHROMENES, 2H-CHROMENES, CHROMANS AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2003-11-27 WO disclosed
CN-1446215-A Heterocyclylalkyl azole derivatives and use thereof as pesticidal agents BAYER CROPSCIENCE GMBH (DE) 2003-10-01 CN disclosed
EP-1345906-A2 METHOD FOR PRODUCING 4-HALOALKYL NICOTINE NITRILES Bayer CropScience GmbH (DE) 2003-09-24 EP disclosed
EP-1065198-B1 Process for the production of Malononitrile DEGUSSA CORP (US) 2003-09-17 EP disclosed
EP-1338336-A1 CATALYSTS COMPRISING N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2003-08-27 EP disclosed
US-20030157672-A1 Nitrilase from rhodococcus rhodochrous ncimb 11216 BASF AKTIENGESELLSCHAFT (DE) 2003-08-21 US disclosed
EP-1327631-A2 Fused heterocyclic compounds, their production and use as angiotensin II antagonists Takeda Chemical Industries, Ltd. (JP) 2003-07-16 EP disclosed
EP-0518033-B1 Fused heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-02 EP disclosed
EP-0952144-B1 Processes for preparing pesticidal intermediates BAYER AGRICULTURE LTD (GB) 2003-06-18 EP disclosed
US-20030109711-A1 Process for the preparation of 4-haloalkylnicotinonitriles BAYER CROPSCIENCE AG (DE) 2003-06-12 US disclosed
EP-1309588-A1 HETEROCYCLYLALKYL AZOLE DERIVATIVES AND USE THEREOF AS PESTICIDAL AGENTS Bayer CropScience GmbH (DE) 2003-05-14 EP disclosed
WO-2003035077-A1 N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2003-05-01 WO disclosed
CN-1411506-A Nitrilase from rhodococcus rhodochrous NCIMB11216 BASF AG (DE) 2003-04-16 CN disclosed
US-6541640-B2 Intermediates in preparation of pesticides, by reacting a 3-amino-1-haloalkyl-2-propen-1-one in a condensation reaction with nitriles such as cyanoacetylene and subjecting the resulting compound to a ring closure reaction AVENTIS CROPSCIENCE GMBH (DE) 2003-04-01 US disclosed
CN-1395507-A Catalysts comprising N-substituted cyclic imides and processes for prepairing organic compounds with catalysts DAICEL CHEM (JP) 2003-02-05 CN disclosed
US-20030013603-A1 Catalyst comprising n-substituted cylic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-01-16 US disclosed
EP-1268757-A1 NITRILASE FROM RHODOCOCCUS RHODOCHROUS NCIMB 11216 BASF AKTIENGESELLSCHAFT (DE) 2003-01-02 EP disclosed
CN-1094123-C Noval process for synthesizing 3,3-dialkoxyl propionitrile GUANGZHOU CHEMISTRY INST CAS (CN) 2002-11-13 CN disclosed
CN-1094123-C Noval process for synthesizing 3,3-dialkoxyl propionitrile GUANGZHOU CHEMISTRY INST CAS (CN) 2002-11-13 CN disclosed
US-6458903-B1 CONTROLLING AN ATOM TRANSFER IN RADICAL POLYMERIZATION KANEKA CORPORATION (JP) 2002-10-01 US disclosed
US-20020132813-A1 Heterocyclylalkylazole derivatives and their use as pesticides AVENTIS CROPSCIENCE GMBH (DE) 2002-09-19 US disclosed
US-20020128485-A1 Processes for preparing pesticidal intermediates MERIAL LIMITED 2002-09-12 US disclosed
US-20020128149-A1 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-09-12 US disclosed
EP-1238704-A2 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst Daicel Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
US-20020087004-A1 Process for the preparation of 4-Haloalkylnicotinonitriles BAYER CROPSCIENCE AG (DE) 2002-07-04 US disclosed
WO-2002048111-A2 METHOD FOR PRODUCING 4-HALOALKYL NICOTINE NITRILES BAYER CROPSCIENCE GMBH (DE) 2002-06-20 WO disclosed
US-6392081-B1 REACTING A NITRILE COMPOUND CONTAINING ACTAL GROUPS WITH ARYLHYDRAZINE; OXIDATION AVENTIS AGRICULTURE LTD. (GB) 2002-05-21 US disclosed
US-6353126-B1 DEHYDRATION OF CYANOACETAMIDE EMPLOYS CYANURIC CHLORIDE IN THE PRESENCE OF A CATALYTIC AMOUNT OF N,N-DIMETHYLFORMAMIDE AND IN A POLAR SOLVENT THAT IS REMOVED BY VACUUM DISTILLATION CREANOVA INC. 2002-03-05 US disclosed
WO-2002012229-A1 HETEROCYCLYLALKYL AZOLE DERIVATIVES AND USE THEREOF AS PESTICIDAL AGENTS BAYER CROPSCIENCE GMBH (DE) 2002-02-14 WO disclosed
WO-2001064857-A1 NITRILASE FROM RHODOCOCCUS RHODOCHROUS NCIMB 11216 BASF AKTIENGESELLSCHAFT (DE) 2001-09-07 WO disclosed
CN-1303396-A Polymerization method KANEGAFUCHI CHEMICAL IND (JP) 2001-07-11 CN disclosed
CN-1297429-A Process for preparing pesticidal intermediates AFANTI AGRICULTURE LTD (GB) 2001-05-30 CN disclosed
EP-1090930-A1 POLYMERIZATION METHOD KANEKA CORPORATION (JP) 2001-04-11 EP disclosed
EP-1073627-A1 PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES AVENTIS AGRICULTURE LTD. (GB) 2001-02-07 EP disclosed
EP-1065198-A1 Process for the production of Malononitrile Creanova Inc. (US) 2001-01-03 EP disclosed
US-6159901-A 6-phenoxy picolinic acid alkylidene hydrazide derivative, process for producing the same and herbicide using the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-12 US disclosed
EP-1020444-A1 6-PHENOXYPICOLINIC ACID, ALKYLIDENEHYDRAZIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed
CN-1243121-A Noval process for synthesizing 3,3-dialkoxyl propionitrile GUANGZHOU CHEMISTRY INST CAS (CN) 2000-02-02 CN disclosed
CN-1243121-A Noval process for synthesizing 3,3-dialkoxyl propionitrile GUANGZHOU CHEMISTRY INST CAS (CN) 2000-02-02 CN disclosed
EP-0970029-A1 PROCESS FOR THE PREPARATION OF 9-DEAZAGUANINE DERIVATIVES BIOCRYST PHARMACEUTICALS INC. (US) 2000-01-12 EP disclosed
CN-1239472-A Process for prepn. of 9-deazaguanine derivatives BIOCRYST PHARM INC (US) 1999-12-22 CN disclosed
WO-1999054288-A1 PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES AVENTIS AGRICULTURE LTD. (GB) 1999-10-28 WO disclosed
EP-0952144-A1 Processes for preparing pesticidal intermediates RHONE-POULENC AGRICULTURE LTD. (GB) 1999-10-27 EP disclosed
US-5932676-A ORGANOSILICON POLYMERS; STORAGE STABILITY; COATINGS FOR ELECTRONICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-08-03 US disclosed
US-5773624-A Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives KATAYAMA SEIYAKUSYO CO., LTD. (JP) 1998-06-30 US disclosed
EP-0814130-A2 Liquid coating composition for forming silicon-containing coating film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-29 EP disclosed
EP-0795551-A1 Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives KATAYAMA SEIYAKUSYO CO. Ltd. (JP) 1997-09-17 EP disclosed
US-5663181-A Naphthyridine derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as antiproliferative drugs LABORATOIRES UPSA (FR) 1997-09-02 US disclosed
US-5650511-A MULTISTAGE REACTION OF ALDEHYDE OR KETONE WITH NITRILE GROUP TO FORM ENAMINE, REACTION OF ENAMINE WITH BASE TO FORM PYRROLE, THEN REACTION BIOCRYST PHARMACEUTICALS, INC. (US) 1997-07-22 US disclosed
WO-1997021653-A1 PROCESS FOR THE PREPARATION OF 9-DEAZAGUANINE DERIVATIVES BIOCRYST PHARMACEUTICALS, INC. (US) 1997-06-19 WO disclosed
CN-1125444-A Naphthyridine derivatives, process for their preparation and pharmaceutical compositions containing them, especially useful as antiproliferative agents UNION PHARMA SCIENT APPL (FR) 1996-06-26 CN disclosed
EP-0705261-A1 ANTIPROLIFERATIVE NAPHTHYRIDINES LABORATOIRES UPSA (FR) 1996-04-10 EP disclosed
US-5389641-A Fused heterocyclic compounds, having angiotensin II antagonistic activity TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
WO-1995000513-A1 ANTIPROLIFERATIVE NAPHTHYRIDINES LABORATOIRES UPSA (FR) 1995-01-05 WO disclosed
US-5364860-A Naphthyridine compounds which inhibit tyrosine kinase and their pharmaceutical compositions LABORATOIRES UPSA (FR) 1994-11-15 US disclosed
EP-0358044-B1 Process to precipitate cytosin from alkaline solutions, with sulfuric acid BOEHRINGER INGELHEIM KG (DE) 1994-01-26 EP disclosed
US-5214184-A METHOD OF PRODUCING CARBONIC ACID DIESTER UBE INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0518033-A1 Fused heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-16 EP disclosed
EP-0503618-A1 Method of producing carbonic acid diester UBE INDUSTRIES, LTD. (JP) 1992-09-16 EP disclosed
EP-0279556-B1 PROCESS FOR PRODUCING 2-HYDROXY-METHYLENE-3,3-DIALKOXYPROPANE-NITRILE ALKALI METAL SALT AND PROCESS FOR OBTAINING ALCOHOLIC SLURRY OF SAID COMPOUND FROM ITS SYNTHETIC REACTION MIXTURE UBE INDUSTRIES, LTD. (JP) 1991-11-27 EP disclosed
US-4978766-A Process for producing 2-hydroxymethylene-3,3-dialkoxypropanenitrile alkali metal salt and process for obtaining alcoholic slurry of said compound from its synthetic reaction mixture UBE INDUSTRIES, LTD. (JP) 1990-12-18 US disclosed
EP-0358044-A2 Process to precipitate cytosin from alkaline solutions, with sulfuric acid BOEHRINGER INGELHEIM KG (DE) 1990-03-14 EP disclosed
EP-0279556-A1 Process for producing 2-hydroxy-methylene-3,3-dialkoxypropane-nitrile alkali metal salt and process for obtaining alcoholic slurry of said compound from its synthetic reaction mixture UBE INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed
EP-0087585-B1 METHOD FOR THE PREPARATION OF 3-ALKOXY-ACRYLONITRILES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1985-11-06 EP disclosed
US-4541960-A Method for preparing cyanacetaldehyde acetals DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1985-09-17 US disclosed
US-4525310-A Method of preparing 3-alkoxy acrylonitriles DYNAMIT NOBEL AG (DE) 1985-06-25 US disclosed
US-4504422-A FROM OLEFIN, ALCOHOL, PLATINUM GROUP CATALYST, NITRITE UBE INDUSTRIES, LTD. (JP) 1985-03-12 US disclosed
US-4504421-A NITRITE, PLATINUM GROUP METAL OR SALT, HALIDE, IRON COMPOUND UBE INDUSTRIES, LTD. (JP) 1985-03-12 US disclosed
US-4501705-A REACT OLEFIN AND ALCOHOL IN PRESENCE OF ESTER NITRITE, PLATINUM GROUP CATALYSTS AND COPPER HALIDE UBE INDUSTRIES, LTD. (JP) 1985-02-26 US disclosed
EP-0055108-B1 PROCESS FOR PRODUCING AN ACETAL UBE INDUSTRIES, LTD. (JP) 1984-09-05 EP disclosed
JP-S5826855-A PRODUCTION OF 3-ALKOXY-2-PROPENENITRILE UBE IND LTD 1983-02-17 JP disclosed
EP-0055108-A1 Process for producing an acetal UBE INDUSTRIES, LTD. (JP) 1982-06-30 EP disclosed
US-4273931-A Reduction of alkyl esters of carbonic-carboxylic anhydrides to alcohols ISTITUTO CHEMIOTERAPICO ITALIANO, S.P.A. (IT) 1981-06-16 US disclosed
US-4273931-A Reduction of alkyl esters of carbonic-carboxylic anhydrides to alcohols ISTITUTO CHEMIOTERAPICO ITALIANO, S.P.A. (IT) 1981-06-16 US disclosed