Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNG | P07510 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRND | Q07001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556129 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2556655 | 0.89 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL2557988 | 0.89 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL2561385 | 0.87 | CHRNB2 (0.42) | CHRNB2CHRNA4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2555955 | 0.87 | CHRNB2 (0.42) | CHRNB2CHRNA4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2562799 | 0.79 | CSNK1D (0.35) | ALDH1A1L3MBTL1KDM4EKCNJ1 | |
| SCHEMBL2561169 | 0.79 | CSNK1D (0.35) | ALDH1A1L3MBTL1KDM4EKCNJ1 | |
| SCHEMBL17161132 | 0.78 | NOTUM (0.41) | ALDH1A1L3MBTL1KDM4EKCNJ1 | |
| SCHEMBL29957248 | 0.78 | NOTUM (0.41) | ALDH1A1L3MBTL1KDM4EKCNJ1 | |
| SCHEMBL15331773 | 0.78 | SYK (0.38) | ALDH1A1L3MBTL1KDM4EKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |