Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 1/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 1/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 1/20 | 1.00 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 8/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461423 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| Water SCHEMBL28234954 | 0.98 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| Benzene SCHEMBL11180826 | 0.98 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| Hydrochloric Acid SCHEMBL6189484 | 0.98 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| Quinoxaline SCHEMBL27447866 | 0.92 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| SCHEMBL28863471 | 0.87 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| Acetic Acid SCHEMBL29289401 | 0.87 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| SCHEMBL28062169 | 0.85 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DPI4KA | |
| SCHEMBL28062205 | 0.82 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Ethoxycarbonyl Group SCHEMBL27845970 | 0.79 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2165 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504613-B | Coumarin derivative containing quinazoline unit as well as preparation method and application thereof | 江苏海洋大学 | 2026-02-27 | — | — | CN | claimed |
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | claimed |
| CN-119504613-A | Novel coumarin derivative containing quinazoline unit, and preparation method and application thereof | 江苏海洋大学 | 2025-02-25 | — | — | CN | claimed |
| CN-118561810-A | Medicament for preventing and treating tea tree fungal diseases and preparation method thereof | 贵州大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118146226-A | Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof | 贵州大学 | 2024-06-07 | — | — | CN | claimed |
| CN-117946083-A | Quinazoline derivative containing piperonal as well as synthesis method and application thereof | 贵州大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116120242-B | Quick detection device for fenazaquin in tea, and preparation and application thereof | 佛山职业技术学院 | 2023-06-27 | — | — | CN | claimed |
| CN-116120242-A | Quick detection device for fenazaquin in tea, and preparation and application thereof | 佛山职业技术学院 | 2023-05-16 | — | — | CN | claimed |
| CN-115785003-A | Preparation method of 4-chloroquinazoline | 上海泰坦科技股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-111362957-B | Preparation method of icotinib key intermediate | 上海百利佳生医药科技有限公司 | 2022-02-18 | — | — | CN | claimed |
| US-6126917-A | RADIOLABELED COMPOUND | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2000-10-03 | — | — | US | claimed |
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | claimed |
| EP-0537600-B1 | An improved process for the preparation of 4-haloquinazolines | DOWELANCO (US) | 1997-07-16 | — | — | EP | claimed |
| CN-1121071-A | Synthesis and activity of 4-aryl oxime ether quinazoline compound | UNIV NANKAI (CN) | 1996-04-24 | — | — | CN | claimed |
| US-5214144-A | Halogenation of corresponding hydroxy derivative, simplified process | DOWELANCO (US) | 1993-05-25 | — | — | US | claimed |
| EP-0537600-A1 | An improved process for the preparation of 4-haloquinazolines | DOWELANCO (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0380264-A2 | Halogenation process | DowElanco (US) | 1990-08-01 | — | — | EP | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-1035825-A | Quinazoline derivant | LILLY CO ELI (US) | 1989-09-27 | — | — | CN | claimed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | claimed |