Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 8/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384799 | 0.88 | METAP1 (0.61) | METAP1LMNAMEN1KMT2AHTT | |
| SCHEMBL25463096 | 0.84 | MEN1 (0.57) | METAP1LMNAMEN1KMT2AHTT | |
| SCHEMBL17275213 | 0.84 | METAP1 (0.57) | METAP1LMNAMEN1KMT2AHTT | |
| SCHEMBL16404333 | 0.84 | METAP1 (0.61) | METAP1LMNAMEN1KMT2AHTT | |
| Benzene SCHEMBL11180826 | 0.84 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DMETAP1 | |
| SCHEMBL29461423 | 0.82 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DMETAP1 | |
| SCHEMBL25620 | 0.82 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DMETAP1 | |
| Hydrochloric Acid SCHEMBL6189484 | 0.80 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Water SCHEMBL28234954 | 0.80 | PDE4A (0.95) | PDE4APDE4BPDE4CPDE4DMETAP1 | |
| SCHEMBL28062169 | 0.80 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105520951-B | The polysaccharid derivative of toroidal shell containing quinazoline and preparation method and bioactivity | 鲁东大学 | 2018-09-18 | — | — | CN | disclosed |
| CN-105520951-A | Chitosan derivative containing quinazoline ring as well as preparation method and biological activity | UNIV LUDONG | 2016-04-27 | — | — | CN | disclosed |