Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849177 | 0.85 | MEN1 (0.59) | MEN1KMT2APOLBALOX15ALDH1A1 | |
| SCHEMBL2096761 | 0.83 | MEN1 (0.73) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL22407740 | 0.83 | MEN1 (0.73) | MEN1KMT2APOLBRAB9ANPC1 | |
| Pincainide SCHEMBL2110148 | 0.83 | MEN1 (0.73) | MEN1KMT2APOLBRAB9ANPC1 | |
| Pyrrocaine SCHEMBL25718 | 0.81 | MEN1 (0.70) | MEN1KMT2APOLBRAB9AALOX15 | |
| Pyrrocaine SCHEMBL10757216 | 0.80 | MEN1 (0.68) | MEN1KMT2APOLBRAB9AALOX15 | |
| SCHEMBL24849204 | 0.79 | MEN1 (0.52) | MEN1KMT2APOLBRAB9AALOX15 | |
| Pyrrocaine SCHEMBL1651381 | 0.79 | MEN1 (0.67) | MEN1KMT2APOLBRAB9AALOX15 | |
| SCHEMBL24849222 | 0.77 | POLB (0.51) | MEN1KMT2APOLBALOX15ALDH1A1 | |
| SCHEMBL24177661 | 0.77 | HTT (0.60) | MEN1KMT2APOLBRAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183169-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG | Sichuan Academy Of Medical Sciences · Sichuan Provincial People's Hospital (CN) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183169-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG | NOTUM, BYSL, TYR | MEN1 2637/4885KMT2A 2785/4885POLB 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.