Pyrrocaine

Pyrrocaine

SCHEMBL25718

Cc1cccc(C)c1NC(=O)CN1CCCC1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
POLB P06746 3/20 0.70
TDP1 Q9NUW8 1/20 0.67
ALDH1A1 P00352 3/20 0.61
RAB9A P51151 1/20 0.60
DRD4 P21917 1/20 0.57
ATM Q13315 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALOX15 P16050 1/20 0.56
KCNH2 Q12809 2/20 0.56
MLNR O43193 1/20 0.56
NR1I2 O75469 1/20 0.56
USP2 O75604 1/20 0.56
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
PGR P06401 1/20 0.56
ADRB1 P08588 1/20 0.56
CYP3A4 P08684 1/20 0.56
ADRA2A P08913 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pincainide SCHEMBL2110148 0.98 MEN1 (0.73) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL22407740 0.98 MEN1 (0.73) MEN1KMT2APOLBTDP1ALDH1A1
Pyrrocaine SCHEMBL10757216 0.98 MEN1 (0.68) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL2096761 0.98 MEN1 (0.73) MEN1KMT2APOLBTDP1ALDH1A1
Pyrrocaine SCHEMBL1651381 0.97 MEN1 (0.67) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL2327539 0.93 ALDH1A1 (0.64) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL6258331 0.89 ALOX15 (0.67) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL22407703 0.89 MEN1 (0.60) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL8556384 0.88 MEN1 (0.60) MEN1KMT2APOLBTDP1ALDH1A1
SCHEMBL6261397 0.88 ALOX15 (0.74) MEN1KMT2APOLBTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3024 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 US claimed
US-20250360095-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN TREATING PAIN TAIWAN LIPOSOME COMPANY, LTD. (TW) 2025-11-27 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-20250319025-A9 COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-16 US claimed
US-12409154-B2 Pharmaceutical compositions for use in treating pain TAIWAN LIPOSOME COMPANY, LTD. (TW) 2025-09-09 US claimed
EP-4578441-A1 TREATMENT OF LOCALIZED PAIN PlantTec Medical GmbH (DE) 2025-07-02 EP claimed
US-20250205278-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING ABBOTT NICHOLAS L (US) 2025-06-26 US claimed
WO-2025128639-A1 HYDROGELS COMPRISING PROTEIN-STABILIZED NANOPARTICLES FOR EXTENDED RELEASE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-06-19 WO claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 US claimed
EP-0932416-A2 METHOD AND POTENTIATED COMPOSITION FOR TREATING MIGRAINE Algos Pharmaceutical Corporation (US) 1999-08-04 EP claimed
EP-0914106-A1 PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE RHODES, John (GB) 1999-05-12 EP claimed
WO-1999013865-A1 SUSTAINED-RELEASE LIPOSOMAL ANESTHETIC COMPOSITIONS DEPOTECH CORPORATION (US) 1999-03-25 WO claimed
WO-1998041171-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE GALIN MILES A (US) 1998-09-24 WO claimed
US-5776952-A Method and composition for topical therapy of back pain and muscle tension AMERICAN PHARMED LABS, INC. (US) 1998-07-07 US claimed
WO-1998015275-A2 METHOD AND POTENTIATED COMPOSITION FOR TREATING MIGRAINE ALGOS PHARMACEUTICAL CORPORATION (US) 1998-04-16 WO claimed
WO-1997044021-A1 PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE RHODES JOHN (GB) 1997-11-27 WO claimed
WO-1995009613-A1 CONTROLLED RELEASE MICROSPHERES CHASIN MARK (US) 1995-04-13 WO claimed
US-5209724-A Buffering local anesthetic, reducing pain and irritation on injection M.D., INC. 1993-05-11 US claimed
US-4866050-A TISSUE PENETRATING DRUG DELIVERY BEN AMOZ DANIEL (US) 1989-09-12 US claimed