Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077841 | 0.83 | MEN1 (0.52) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL167233 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL15079242 | 0.81 | KMT2A (0.49) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL3707818 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3707545 | 0.80 | IGF1R (0.48) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL3699244 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15052949 | 0.79 | IGF1R (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15053716 | 0.79 | IGF1R (0.47) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15052734 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL15052409 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028106-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2012-03-08 | — | — | WO | disclosed |