SCHEMBL256208

SCHEMBL256208

Cc1cccc2c1ccn2C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
RHEB Q15382 1/20 0.49
NQO2 P16083 2/20 0.48
HSD11B1 P28845 4/20 0.47
CYP2A6 P11509 2/20 0.46
CYP1A2 P05177 1/20 0.46
ALKBH5 Q6P6C2 1/20 0.44
FTO Q9C0B1 1/20 0.44
ASH1L Q9NR48 1/20 0.41
FABP4 P15090 1/20 0.40
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12309486 0.81 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTRXFP1HTR2A
SCHEMBL5102197 0.76 HTR2A (0.51) ALDH1A1KDM4EHTR2AHTR2CNQO2
SCHEMBL4071478 0.76 HTR2A (0.51) ALDH1A1KDM4EHTR2AHTR2CNQO2
SCHEMBL19089435 0.76 HTR2A (0.47) ALDH1A1KDM4EHTR2AHTR2CNQO2
SCHEMBL10441151 0.76 HTR2A (0.47) ALDH1A1KDM4EHTR2AHTR2CNQO2
SCHEMBL2435580 0.76 RHEB (0.66) ALDH1A1KDM4EMAPTRXFP1HTR2A
SCHEMBL21893432 0.76 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTRXFP1HTR2A
SCHEMBL21863280 0.76 MAPT (0.48) ALDH1A1KDM4EMAPTRXFP1RHEB
SCHEMBL7964114 0.76 RHEB (0.77) ALDH1A1KDM4EMAPTRXFP1HTR2C
SCHEMBL1138076 0.76 KDM4E (0.48) ALDH1A1KDM4EMAPTRXFP1RHEB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 435 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903161-A Tetrathiodiindole compound and derivative, synthetic method and application thereof 衡阳师范学院 2024-04-19 CN claimed
CN-117209488-A Alkaloid barakacin derivative, synthesis thereof and application thereof in prevention and treatment of plant virus and germ diseases 天津师范大学 2023-12-12 CN claimed
CN-116969967-A Synthesis method of polysubstituted-5, 10-dihydro [1,2,3,4] tetrathio [5,6-b:7,8-b' ] diindole and derivative 衡阳师范学院 2023-10-31 CN claimed
CN-116813639-A Synthesis method of polysubstituted [1,2,3,4,5] pentathio [6,7-b ] indole and derivative 衡阳师范学院 2023-09-29 CN claimed
CN-113121403-B Method for preparing tri-substituted indole compound by one-step method 江苏科技大学 2022-12-30 CN claimed
CN-113564623-A Method for preparing isatin compound by electrochemically oxidizing N-substituted indole derivative 福建师范大学 2021-10-29 CN claimed
CN-104788359-A Synthesis method of copper-promoted 3-cyano-substituted-indole compound UNIV HUNAN 2015-07-22 CN claimed
CN-104387407-A 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof as well as synthesis method of 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof UNIV XIANGTAN 2015-03-04 CN claimed
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
EP-4580621-A2 T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS The Broad Institute, Inc. (US) 2025-07-09 EP disclosed
CN-120118016-A 1, 1-Di (indolyl) olefin compound and preparation method and application thereof 华南理工大学 2025-06-10 CN disclosed
CN-120091815-A T-type voltage-gated calcium channel enhancer 广泛研究所股份有限公司 2025-06-03 CN disclosed
US-12319946-B2 Methods for producing modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-06-03 US disclosed
CN-115974845-B Preparation method of Ornitinib intermediate 奥锐特药业股份有限公司 2024-09-20 CN disclosed
WO-2003088897-A2 FAB I INHIBITORS AFFINIUM PHARMACEUTICALS, INC. (CA) 2003-10-30 WO disclosed
EP-1226138-A4 FAB I INHIBITORS SMITHKLINE BEECHAM CORP (US) 2003-03-05 EP disclosed
EP-1249450-A1 BENZIMIDAZOLE DERIVATIVES TEIJIN LIMITED (JP) 2002-10-16 EP disclosed
EP-1226138-A1 FAB I INHIBITORS SmithKline Beecham Corporation (US) 2002-07-31 EP disclosed
WO-2001027103-A1 FAB I INHIBITORS SMITHKLINE BEECHAM CORPORATION (GB) 2001-04-19 WO disclosed
US-4443615-A ANILINE, GLYCOL OR EPOXIDE, SILICA AND/OR ALUMINA CATALYST TANABE SEIYAKU CO., LTD. (JP) 1984-04-17 US disclosed