Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624204 | 0.85 | KDM4C (0.39) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL25624097 | 0.84 | KDM4C (0.38) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL25268778 | 0.80 | KDM4C (0.44) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL19223858 | 0.80 | KDM4C (0.44) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL31052348 | 0.79 | KDM4C (0.47) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL16401219 | 0.75 | KDM4C (0.46) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL25273570 | 0.74 | NPC1 (0.45) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL30542325 | 0.74 | NPC1 (0.45) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL1452396 | 0.71 | KDM4C (0.43) | KDM4CL3MBTL1NPC1RAB9AICAM1 | |
| SCHEMBL31221861 | 0.71 | KDM4C (0.43) | KDM4CL3MBTL1NPC1RAB9AICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |