Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624204 | 0.85 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL25624099 | 0.84 | KDM4C (0.41) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL25219615 | 0.82 | KDM4C (0.40) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL19223858 | 0.80 | KDM4C (0.44) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL31052348 | 0.77 | KDM4C (0.47) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL25221157 | 0.75 | DUT (0.31) | — | |
| SCHEMBL30542325 | 0.73 | NPC1 (0.45) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL25273570 | 0.73 | NPC1 (0.45) | KDM4CNPC1RAB9AL3MBTL1ICAM1 | |
| SCHEMBL16401219 | 0.73 | KDM4C (0.46) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL1054538 | 0.73 | L3MBTL1 (0.37) | KDM4CNPC1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |