Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.63 |
| ▸ | UNG | P13051 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560353 | 0.88 | TRIM24 (0.63) | TRIM24TRIM33UNGAKR1C3AKR1C2 | |
| SCHEMBL2560514 | 0.85 | TRIM24 (0.67) | TRIM24TRIM33UNGERN1ALDH1A1 | |
| SCHEMBL15330022 | 0.83 | ALDH1A1 (0.56) | TRIM24TRIM33UNGAKR1C3AKR1C2 | |
| SCHEMBL2561660 | 0.82 | TRIM24 (0.63) | TRIM24TRIM33UNGAKR1C3AKR1C2 | |
| SCHEMBL505879 | 0.81 | AKR1C3 (0.56) | AKR1C3AKR1C2RARBALDH1A1ADH5 | |
| SCHEMBL29473809 | 0.81 | RARB (0.56) | AKR1C3AKR1C2RARBALDH1A1ADH5 | |
| SCHEMBL2041007 | 0.81 | RARB (0.56) | AKR1C3AKR1C2RARBALDH1A1ADH5 | |
| SCHEMBL3642916 | 0.80 | AKR1C3 (0.59) | AKR1C3AKR1C2ERN1RARBALDH1A1 | |
| SCHEMBL2556752 | 0.79 | TRIM24 (0.63) | TRIM24TRIM33UNGERN1ALDH1A1 | |
| SCHEMBL2587878 | 0.79 | UNG (0.79) | TRIM24TRIM33UNGERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |