Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15214740 | 1.00 | CYBB (0.32) | CYBBNOX5NOX1 | |
| SCHEMBL14682739 | 0.86 | CYBB (0.31) | CYBBNOX5NOX1 | |
| SCHEMBL12287461 | 0.82 | KDM1A (0.31) | — | |
| SCHEMBL2562384 | 0.79 | CACNB4 (0.35) | — | |
| SCHEMBL440184 | 0.79 | CYP3A4 (0.31) | — | |
| SCHEMBL4601117 | 0.76 | POLB (0.33) | — | |
| SCHEMBL10098744 | 0.75 | — | — | |
| SCHEMBL12855001 | 0.70 | MEN1 (0.33) | — | |
| SCHEMBL14682738 | 0.67 | CACNB4 (0.34) | — | |
| SCHEMBL14682734 | 0.67 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316809-B1 | Process for the preparation of benzonorbornane derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| EP-2560960-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2316813-B1 | Process for the preparation of amines | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-03 | — | — | EP | disclosed |
| EP-2560960-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2011131544-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-10-27 | — | — | WO | disclosed |
| US-7781615-B2 | Process for the preparation of amines | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | HRH3, PAH, C1R | CYBB 871/4885NOX5 644/4885NOX1 461/4885 |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | CBR3, F12, CBR1 | CYBB 347/4885NOX5 397/4885NOX1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.