⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624105 | 0.79 | — | — | |
| SCHEMBL25627483 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL25624691 | 0.75 | PDE4B (0.34) | — | |
| SCHEMBL25624233 | 0.68 | LRRK2 (0.30) | — | |
| SCHEMBL25613023 | 0.67 | ADRA2A (0.31) | — | |
| SCHEMBL25624234 | 0.66 | PIM1 (0.32) | — | |
| SCHEMBL25624107 | 0.66 | — | — | |
| SCHEMBL25626737 | 0.64 | LRRK2 (0.34) | — | |
| SCHEMBL25624235 | 0.64 | — | — | |
| SCHEMBL25624159 | 0.62 | LRRK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |