Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25638888 | 1.00 | FPR3 (0.42) | FPR3FPR2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25633647 | 1.00 | FPR3 (0.42) | FPR3FPR2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30399847 | 0.87 | EPHX2 (0.45) | FPR3FPR2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL25615095 | 0.87 | EPHX2 (0.45) | FPR3FPR2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL25638890 | 0.87 | EPHX2 (0.45) | FPR3FPR2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL25638931 | 0.81 | EPHX1 (0.42) | SMN1; SMN2EPHX1MAPTCDK2GSK3B | |
| SCHEMBL25638932 | 0.81 | EPHX1 (0.42) | SMN1; SMN2EPHX1MAPTCDK2GSK3B | |
| SCHEMBL25618724 | 0.81 | EPHX1 (0.40) | SMN1; SMN2RAB9ANPC1TRPV1EPHX1 | |
| SCHEMBL25882159 | 0.81 | FPR3 (0.41) | FPR3FPR2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25638926 | 0.80 | EPHX1 (0.41) | SMN1; SMN2RAB9ANPC1EPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091554-A1 | NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS | ICAGEN, LLC (US) | 2023-05-25 | — | — | WO | disclosed |