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FPR3

N-formyl peptide receptor 3 · P25089 · FPR3 on Sugi Atlas →

24,325 patent compounds predicted against FPR3, 16,106 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL855458 SCHEMBL855458 0.66 20/20
SCHEMBL855276 SCHEMBL855276 0.73 19/20
SCHEMBL855286 SCHEMBL855286 0.70 19/20
SCHEMBL855312 SCHEMBL855312 0.65 18/20
SCHEMBL727380 SCHEMBL727380 0.76 17/20
SCHEMBL857603 SCHEMBL857603 0.68 17/20
SCHEMBL857340 SCHEMBL857340 0.66 17/20
SCHEMBL856945 SCHEMBL856945 0.65 17/20
SCHEMBL856167 SCHEMBL856167 0.58 17/20
SCHEMBL727272 SCHEMBL727272 0.72 16/20
SCHEMBL855932 SCHEMBL855932 0.70 16/20
SCHEMBL855746 SCHEMBL855746 0.68 16/20
SCHEMBL857151 SCHEMBL857151 0.67 16/20
SCHEMBL855247 SCHEMBL855247 0.60 16/20
SCHEMBL856545 SCHEMBL856545 0.76 15/20
SCHEMBL855204 SCHEMBL855204 0.71 15/20
SCHEMBL855335 SCHEMBL855335 0.61 15/20
SCHEMBL856708 SCHEMBL856708 0.76 14/20
SCHEMBL855038 SCHEMBL855038 0.66 14/20
SCHEMBL855173 SCHEMBL855173 0.60 14/20

Clinical trials — most relevant to FPR3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion PHASE4COMPLETED
Ramatroban/Montelukast Versus Montelukast/Placebo on the Early Allergic Reaction in Asthma Sensitive to House Dust Mite PHASE2/PHASE3WITHDRAWN
Montelukast for Early Life Wheezing PHASE2/PHASE3COMPLETED
Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block PHASE2/PHASE3COMPLETED
Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids PHASE2/PHASE3COMPLETED
Omega-3 Fatty Acids for Smoking Cessation in Pregnancy PHASE2COMPLETED
Electrophilic Fatty Acid Derivatives in Asthma PHASE1COMPLETED
Pro-Resolving Mediators in Acute Inflammation in Humans EARLY_PHASE1COMPLETED
The Severe Asthma Research Program III-Boston Clinical Site nanCOMPLETED
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation nanUNKNOWN
In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors nanCOMPLETED
Lipid Mediators in Multiple Sclerosis nanCOMPLETED
NETs: Protection or Harm in Neonatal Inflammation or Infection nanRECRUITING
Evaluation of pentraxin3 as a Marker for Ventilator Associated Pneumonia nanUNKNOWN
Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer. nanUNKNOWN
Study of the Functional Status Neutrophils in Rheumatoid Arthritis Patients to Identify New Biomarkers of Response to Anti-TNFalpha Therapy nanUNKNOWN
Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis nanCOMPLETED
The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain nanUNKNOWN
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity nanNOT_YET_RECRUITING
Gluten-related Disorders in Familial Mediterranean Fever Patients nanCOMPLETED
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis nanWITHDRAWN
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
Clinic Navigation and Home Visits to Improve Guideline-based Care and Outcomes in Low Income Minority Adults With Asthma nanACTIVE_NOT_RECRUITING
Evaluation of DiaSorin LIAISON® PTX3 (Long Pentraxin 3) Assay in Patients With Pneumonia nanCOMPLETED
Pathogenic Mechanisms in C Diff Infection and Colitis nanCOMPLETED
Effects of n3 LC PUFAs on Inflammatory, Immune and Senescence Features in Polyvascular Older Subjects (OMSAGE) nanNOT_YET_RECRUITING
Role of Nox2 in CNI-induced Renal Fibrosis nanCOMPLETED
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients nanCOMPLETED
The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a FPR3 binder may also engage these)

ProteinNameSimilarity
P79243 — 1.000 P79243 →
P79237 — 1.000 P79237 →
P79191 — 0.999 P79191 →
P79235 — 0.998 P79235 →
P79190 — 0.997 P79190 →
FPR2 N-formyl peptide receptor 2 0.996 landscape →
P79178 — 0.996 P79178 →
P79242 — 0.996 P79242 →
P79236 — 0.996 P79236 →
P79189 — 0.995 P79189 →
Q3SXG2 — 0.993 Q3SXG2 →
FPR1 fMet-Leu-Phe receptor 0.992 landscape →
Q05394 — 0.992 Q05394 →
P79176 — 0.992 P79176 →
O08790 — 0.992 O08790 →
P79241 — 0.991 P79241 →
O88536 — 0.991 O88536 →
P79177 — 0.991 P79177 →
P33766 — 0.990 P33766 →
O88537 — 0.990 O88537 →
Q49SP8 — 0.989 Q49SP8 →
Q71MR7 — 0.989 Q71MR7 →
Q49SQ2 — 0.989 Q49SQ2 →
O88416 — 0.989 O88416 →
A4FUQ5 — 0.988 A4FUQ5 →
P0C7U4 — 0.988 P0C7U4 →
Q49SQ1 — 0.987 Q49SQ1 →
Q49SQ3 — 0.987 Q49SQ3 →
P79240 — 0.986 P79240 →
P30993 — 0.985 P30993 →