Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25628756 | 0.84 | HPGD (0.39) | NAMPT | |
| SCHEMBL17888262 | 0.82 | NAMPT (0.53) | NAMPTGRM5CNR2 | |
| SCHEMBL17886600 | 0.80 | NAMPT (0.48) | NAMPTGRM5CNR2 | |
| SCHEMBL21078128 | 0.80 | NAMPT (0.50) | NAMPTGRM5 | |
| SCHEMBL26027615 | 0.75 | NR1H2 (0.37) | GRM5 | |
| SCHEMBL21665288 | 0.74 | MEN1 (0.34) | GRM5 | |
| SCHEMBL21100748 | 0.73 | MAPT (0.45) | — | |
| SCHEMBL17888258 | 0.73 | NAMPT (0.51) | NAMPTGRM5CNR2 | |
| SCHEMBL17660297 | 0.72 | MAPT (0.39) | GRM5 | |
| SCHEMBL104852 | 0.72 | QDPR (0.45) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |