Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455675 | 0.92 | MEN1 (0.51) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL25633236 | 0.81 | HTT (0.52) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL25230824 | 0.80 | MEN1 (0.47) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL31501640 | 0.80 | MEN1 (0.53) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL31501671 | 0.79 | MEN1 (0.49) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL25716737 | 0.79 | HTT (0.46) | MEN1KMT2AHTT | |
| SCHEMBL31501649 | 0.79 | MEN1 (0.48) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL25226781 | 0.78 | MEN1 (0.44) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL25722585 | 0.78 | HTT (0.42) | MEN1KMT2AACHEBACE1HTT | |
| SCHEMBL31501628 | 0.78 | MEN1 (0.49) | MEN1KMT2AACHEBACE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |