Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 14/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25716737 | 0.89 | HTT (0.46) | HTTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL30455675 | 0.87 | MEN1 (0.51) | HTTMEN1KMT2AACHEBACE1 | |
| SCHEMBL25629403 | 0.85 | HTT (0.46) | HTTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL30455740 | 0.84 | HTT (0.44) | HTTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL25222339 | 0.84 | HTT (0.44) | HTTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL19032225 | 0.84 | MEN1 (0.46) | HTTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL25224450 | 0.84 | MEN1 (0.44) | MEN1KMT2ACYP3A4 | |
| SCHEMBL25633293 | 0.83 | HTT (0.52) | HTTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL31501671 | 0.83 | MEN1 (0.49) | HTTMEN1KMT2AACHEBACE1 | |
| Hydrochloric Acid SCHEMBL25278259 | 0.83 | HTT (0.43) | HTTALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |