⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888536 | 0.76 | — | — | |
| SCHEMBL15602625 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL2290730 | 0.74 | — | — | |
| SCHEMBL2294031 | 0.73 | — | — | |
| SCHEMBL24597217 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL16889134 | 0.72 | POLB (0.30) | — | |
| SCHEMBL15984831 | 0.72 | — | — | |
| SCHEMBL2290838 | 0.71 | — | — | |
| SCHEMBL10299189 | 0.71 | — | — | |
| SCHEMBL27269513 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |