Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625703 | 1.00 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL25629580 | 1.00 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL22946822 | 0.79 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL21471482 | 0.78 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL9155932 | 0.78 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL19546305 | 0.77 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL11922102 | 0.77 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL13923320 | 0.77 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL15828974 | 0.77 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL11922094 | 0.77 | MAPK1 (0.55) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192756-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, LLC | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192756-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | CHRNB4, CHRNB3, MC2R | MAPK1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.