Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026070 | 0.83 | BRD4 (0.54) | BRD4GAAGRM1MAPTHPGD | |
| SCHEMBL29673249 | 0.79 | CYP2A6 (0.58) | GAAPKMLOXL2MAPTHPGD | |
| SCHEMBL6683148 | 0.79 | CYP2A6 (0.58) | GAAPKMLOXL2MAPTHPGD | |
| SCHEMBL14721573 | 0.77 | CYP2A6 (0.61) | BRD4GAAGRM1MAPTHPGD | |
| SCHEMBL16381141 | 0.77 | DAO (0.68) | BRD4GAAGRM1LOXL2MAPT | |
| SCHEMBL30636806 | 0.74 | CA12 (0.55) | GAAPKMLOXL2MAPTCA12 | |
| SCHEMBL13802346 | 0.74 | BRD4 (0.59) | BRD4GRM1MAPTHPGDDAO | |
| SCHEMBL28979258 | 0.74 | BRD4 (0.59) | BRD4GAAGRM1HPGDDAO | |
| SCHEMBL7882349 | 0.74 | DAO (0.64) | BRD4GAAGRM1LOXL2MAPT | |
| SCHEMBL27239601 | 0.74 | CA12 (0.55) | GAAPKMLOXL2MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111350-A2 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |