Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 3/20 | 0.54 |
| ▸ | FLT3 | P36888 | 7/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038241 | 0.85 | BRD4 (0.59) | BRD4DAOFLT3CA2KDM4E | |
| SCHEMBL16381141 | 0.81 | DAO (0.68) | BRD4DAOFLT3PDGFRBKDM4E | |
| SCHEMBL14721573 | 0.78 | CYP2A6 (0.61) | BRD4DAOKDM4EALDH1A1GAA | |
| SCHEMBL13802346 | 0.78 | BRD4 (0.59) | BRD4DAOFLT3PDGFRBABL1 | |
| SCHEMBL7882349 | 0.78 | DAO (0.64) | BRD4DAOKDM4EALDH1A1GAA | |
| SCHEMBL8918599 | 0.77 | GRIK1 (0.55) | BRD4DAOKDM4EALDH1A1GAA | |
| SCHEMBL4344151 | 0.76 | FLT3 (0.61) | DAOFLT3PDGFRBKITABL1 | |
| SCHEMBL12348 | 0.76 | CYP2A6 (0.59) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL830973 | 0.75 | CA2 (0.54) | DAOFLT3PDGFRBKITABL1 | |
| SCHEMBL9269640 | 0.75 | AXL (0.64) | BRD4FLT3PDGFRBCA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988093-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |