SCHEMBL25629699

SCHEMBL25629699

c1ccc(-c2cccc(-n3c4ccc(-n5c6ccccc6c6ccccc65)cc4c4ccc5c6ccccc6oc5c43)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 2/20 0.33
ALDH1A1 P00352 5/20 0.32
RXFP1 Q9HBX9 4/20 0.32
PPARG P37231 3/20 0.32
NR2E3 Q9Y5X4 3/20 0.32
NCOR2 Q9Y618 3/20 0.32
LMNA P02545 3/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
POLB P06746 2/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19678241 1.00 KDM4E (0.38) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL26809771 0.96 KDM4E (0.39) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL19653640 0.96 KDM4E (0.39) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL19652809 0.96 KDM4E (0.39) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL19653662 0.95 KDM4E (0.38) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL25629708 0.95 ATM (0.38) KDM4EATML3MBTL1ALDH1A1RXFP1
SCHEMBL24810405 0.94 KDM4E (0.37) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17759587 0.94 KDM4E (0.40) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17760763 0.94 KDM4E (0.40) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17246044 0.94 KDM4E (0.39) KDM4EATML3MBTL1ALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed