SCHEMBL25629708

SCHEMBL25629708

c1ccc(-c2cccc(-n3c4ccc(-n5c6ccccc6c6ccccc65)cc4c4ccc5c6cc(-n7c8ccccc8c8ccccc87)ccc6oc5c43)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
WNK1 Q9H4A3 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19678241 0.95 KDM4E (0.38) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL25629699 0.95 KDM4E (0.38) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL9890217 0.92 KDM4E (0.46) ATMKDM4EL3MBTL1ALDH1A1MEN1
SCHEMBL19653640 0.91 KDM4E (0.39) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL19652809 0.91 KDM4E (0.39) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL26809771 0.91 KDM4E (0.39) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL19653662 0.91 KDM4E (0.38) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL24810405 0.90 KDM4E (0.37) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17759587 0.90 KDM4E (0.40) ATMKDM4EL3MBTL1PLA2G2APLA2G4A
SCHEMBL17760763 0.90 KDM4E (0.40) ATMKDM4EL3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed